Glucose is an important source of energy for the body. The pancreatic hormone insulin plays a key role in the metabolism of the sugar. However, altered blood insulin levels or reduced sensitivity of the cells to the hormone can increase the blood sugar levels and lead to a chronic condition called diabetes. In contrast, excessive use of anti-diabetes medications or fasting can lower the glucose levels in the blood and cause hypoglycemia characterized by dizziness, anxiety, confusion and hunger. Certain natural foods such as Pycnogenol may also promote hypoglycemia. However, you must talk to a doctor before using Pycnogenol to determine if it is right for you.
Pycnogenol
Pycnogenol is the registered trademark of the British company Horphag Research, Ltd., and is a proprietary mixture made up of proanthocyanidins derived from the bark of the Pinus maritime, or the French maritime pine, tree. Pycnogenol supplements are available as capsules, and have been used traditionally to treat several conditions including erectile dysfunction, hypertension, inflammation, venous insufficiency and certain types of cancers. Pycnogenol is also a powerful antioxidant that helps neutralize free oxygen radicals that react with the DNA and proteins of healthy cells and damage them. The recommended dose depends on your age, overall health and condition being treated. Your doctor may help establish a regimen that is appropriate for you.
Role in Hypoglycemia
Pycnogenol can significantly lower the elevated blood glucose levels before meals in laboratory animals, according to a study published in the August 2009 issue of the journal, “Phytotherapy Research.” This may, in turn, lead to hypoglycemia, especially if you use it without diabetes. Another study, this one in the October 2004 issue of the journal, “Life Sciences,” also reveals that supplementation with 100 mg of Pycnogenol for 12 weeks can significantly lower blood glucose levels in Type 2 diabetes patients. Medical journalist and author Robert E. Kowalski also states in the book, “Take the Pressure off Your Heart,” that Pycnogenol lowers the blood sugar levels by overcoming the blocked glucose uptake by the cells in the body. Hence, while Pycnogenol may benefit you if you have diabetes, its overuse may lead to hypoglycemia.
Side Effects
Pycnogenol may make you irritable and lower your energy levels, says the Memorial Sloan-Kettering Cancer Center. It may also cause mouth ulcers, headache and upset stomach. The supplements may also interfere with certain chemotherapy, immunosuppressant and anticoagulant medications.
Precautions
Pycnogenol supplements are easily available at most local pharmacies without a prescription. However, you must talk to a doctor before using them to lower blood sugar levels as it may increase the risk of hypoglycemia.
References
- "Phytotherapy Research"; Pycnogenol Efficiency on Glycaemia, Motor Nerve Conduction Velocity and Markers of Oxidative Stress in Mild Type Diabetes in Rats; S. Jankyova, et al.; August 2009
- "Life Sciences"; Antidiabetic Effect of Pycnogenol French Maritime Pine Bark Extract in Patients with Diabetes Type II; J. Liu X, Wei, et al.; October 2004
- "Take the Pressure Off Your Heart"; Robert E. Kowalski, et al.; 2007
- Memorial Sloan-Kettering Cancer Center: Pine Bark Extract
