Caffeine and nicotine are two of the most commonly used psychoactive substances in the world. While many people use them together without issue, the combined stimulant effects of caffeine and nicotine can cause unpleasant side effects in some cases. To prevent unwanted interactions, ask your doctor before combining caffeine and nicotine if you have a health condition like heart disease.
Features
Nicotine and caffeine are both mild stimulants that increase heart rate, breathing and blood pressure. Nicotine occurs naturally in tobacco, while caffeine is found in many over-the-counter medications and supplements. Caffeine is also a natural component of tea, coffee and the herb guarana. Smoking cessation products like patches and gum often contain small doses of nicotine to help reduce cravings and other smoking withdrawal symptoms.
Side Effects/Risks
The side effects of caffeine and nicotine can overlap somewhat. According to Drugs.com, diarrhea, nervousness and sweating are common side effects of nicotine gum. In large amounts, caffeine may cause similar effects. Both nicotine and caffeine raise blood pressure, body temperature and heart rate, which can cause unpleasant sensations when the substances are combined. Difficulty sleeping, jitteriness and increased heart rate may also occur with either substance or a combination of the two.
Interactions
Taken together, caffeine and nicotine have a combined stimulant effect that is stronger than either substance alone. A study led by Jed Rose and published in the February 1991 issue of "Pharmacology Biochemistry and Behavior" states that caffeine potentiates a rise in diastolic blood pressure caused by tobacco inhalation. While the combination is fine for most healthy people, the effects of caffeine and nicotine on cardiovascular function can be harmful if you have hypertension or a heart condition.
Prevention/Solution
Limiting your use of caffeine and nicotine can help reduce unwanted side effects. If you have high blood pressure or heart disease, ask your physician about the safety of combining caffeine and nicotine. Because of the harmful health effects of tobacco, you may want to consider quitting nicotine altogether. Nicotine replacement products can help reduce withdrawals and increase your chances of success. Seek immediate medical attention if you experience severe headache, rapid heartbeat or other troubling symptoms after combining caffeine and nicotine. These may be signs of cardiovascular complications like high blood pressure or stroke.



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