Caffeine is not known to interact negatively with the medication prednisone. However, this does not necessarily mean you won’t have any adverse reactions while consuming caffeine or taking prednisone. Both caffeine and prednisone may cause a number of unpleasant side effects. They also may interact negatively with other medications or supplements and cause additional undesirable effects. Consult your doctor If you experience any adverse physical reaction after consuming caffeine or taking prednisone.
About Prednisone
Prednisone treats symptoms of low corticosteroid levels, arthritis, severe allergic reactions, multiple sclerosis, lupus and certain types of cancer. It's also used to treat other conditions by changing the way the immune system functions and by reducing swelling and redness. It may be prescribed by itself or in conjunction with other medications.
Prednisone Side Effects
Potential side effects include dizziness, headache, difficulty falling or staying asleep, extreme mood changes, acne, bulging eyes, increased hair growth and red or purple blotches or lines under the skin. Other symptoms include fatigue, weakness, changes in menstruation, decreased libido, increased sweating and heartburn. Serious side effects include vision changes, seizures, depression, flu-like symptoms, signs of infection, difficulty breathing, upset stomach, numbness or burning, shaky hands, muscle twitching, confusion, sudden weight gain, irregular heartbeat, vomiting, rash, hives or itching. Call a doctor immediately if you experience any of these serious side effects. In addition, this medication may increase your risk of osteoporosis or certain types of cancer and may slow the growth and development in children. Talk to your doctor about this concerns before taking the medication.
Prednisone Interactions
Although prednisone does not interact negatively with caffeine, it does interact negatively with many other medications and supplements. Anticoagulants, antifungals, diuretics, HIV protease inhibitors, hormonal contraceptives and diabetes medications are some types of medications that may interact negatively with prednisone. Specific medications with a known interaction to prednisone include amiodarone, aprepitant, aspirin, carbamazepine, cimetidine, clarithromycin, cyclosporine, dexamethasone and fluoxetine. Other medications include fluvoxamine, griseofulvin, lovastatin, nefazodone, nevirapine, phenobarbital, phenytoin, rifabutin, rifampin, sertraline, troleandomycin, verapamil and zafirlukast. St. John’s wort may also interfere with this medication. Always report all of your current medications and supplements to a doctor before starting prednisone.
Caffeine Effects
Caffeine is a common stimulant found in a variety of medications, supplements, food and beverages. It causes an increase in energy, prevents fatigue and may improve cognitive function, but it also may cause several unpleasant side effects. Taking more than 500 mg a day may result in sleep difficulties, gastrointestinal upset, muscle tremors, headaches, increased sweating, irritability, anxiety, nervousness or jitteriness. Although most people can consume about 200 mg a day without experiencing harmful effects, some people are more sensitive to caffeine and will experience them even when small amounts are taken. Caffeine can also cause a physical dependency, which results in unpleasant withdrawal effects when caffeine is not consumed. These withdrawal effects can include irritability, headaches and fatigue.
Caffeine Interactions
While caffeine is unlikely to affect the effectiveness or side effects of prednisone, it does interact negatively with other medications or supplements. Caffeine may affect melatonin, fentanyl, theophylline, rasagiline, tizanide, cimetidine, atazanavir, disulfiram, regadenoson, guaifensin, ephedrine, bendamustine, levobupivacaine, ropivacaine and hydroxyprogesterone. It may also affect lithium, acetaminophen, enoxacin, pimozide, methotrexate, toporecan, thiabendazole, trovafloxacin, angrelide, norfloxacin, dipyridamole, ciprofloxacin. It may also affect mibefradil, fluvoxamine, alosetron, riluzole, grepafloxacin, ramelteon, duloxetine, nicotine, diazepam, nalidixic acid, potassium iodine, deferasirox, clozapine, adenosine, aspirin and asenapine.
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