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Is It Okay to Take Magnesium Oxide With Xanax?

author image Ireland Wolfe
Ireland Wolfe has been writing professionally since 2009, contributing to Toonari Post, Africana Online and Winzer Insurance. She obtained her Bachelor of Arts in psychology and Master of Arts in mental health counseling. She is also a licensed mental health counselor, registered nutritionist and yoga teacher.

Magnesium oxide is a medication that contains the essential element magnesium. Doctors often prescribe magnesium oxide for stomach problems such as heartburn. Alprazolam, sold under the brand name of Xanax, is a benzodiazepine that treats anxiety disorders. These medications have a minor interaction, so you should talk to your doctor before taking both of these medications together.


Magnesium oxide can be prescribed for a number of health reasons. Your doctor may prescribe magnesium oxide as an antacid to treat stomach problems or as a laxative. Generally, you will need the supplement if you are deficient in the essential mineral. Xanax is a prescription medication that helps to reduce excess anxiety, according to PubMed Health. Physicians often prescribe Xanax for general anxiety, panic attacks, agoraphobia and other anxiety conditions.


A minor interaction between magnesium oxide and Xanax exists, according to Drugs.com. Some studies report that antacids, like magnesium oxide, may delay emptying of the stomach, which could affect absorption of Xanax and other benzodiazepines. Drugs.com points out that magnesium oxide does not affect the overall absorption of Xanax, but could delay how long it takes for you to feel the effects of your medication. However, not all studies agree on the possible interaction.


Consult your physician or talk to your pharmacist before taking these two medications together. Your doctor may be able to prescribe a different medication so you can continue to take Xanax. Depending on the reasons you take both medications, you might be able to separate the time you take them so the magnesium oxide will not interfere with absorption. If you have to continue to take both medications, Drugs.com recommends spacing out the medication by two to three hours.


Both of these medications can have side effects. Xanax may be habit-forming, and it is important that you take no more than the prescribed dose. Xanax also can interfere with a number of medications, including some herbal and over-the-counter remedies. Alcohol can interact with Xanax by increasing the drug's side effects. Magnesium oxide can cause cramping and diarrhea. You also can experience an allergic reaction to both medications. If you notice any rashes, hives, dizziness, sudden mood changes or itchiness, tell your doctor immediately.

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