Mixing medications without proper guidance can cause health issues beyond those for which the medications have been prescribed. Using Epsom salts as an internal cleanse or laxative may react negatively with spironolactone, a diuretic. Before taking either medicine, consult with your doctor as to the proper dosage for your condition.
Epsom Salts
Epsom salts are not really salts but actually magnesium sulfate. Magnesium sulfate is easily absorbed through the skin or the digestive system, so caution needs to be taken when introducing this into your healthcare routine. It can be used internally as a laxative for those suffering from constipation or used to evacuate the bowels for tests or surgery. Epsom salts may also be used as an external soak to relieve nerves and relax muscles.
Spironolactone
Spironolactone is a generic name for a medication for people with congestive heart failure. It acts as a diuretic and alleviates fluid retention and swelling. It is also used to treat those with liver cirrhosis, kidney problems, acne, high blood pressure and other conditions. Some of the side effects of spironolactone include diarrhea, muscle pain, weakness, fatigue, nausea and other skin and systemic reactions. Since spironolactone is prescribed by a doctor, don’t attempt to self-medicate using this drug.
Side Effects of Epsom Salts
Even though Epsom salts are available over the counter, there are still some serious side effects that can be detrimental to your overall health. Using too much Epsom salts may trigger complications including nausea, vomiting, dehydration, fainting or even death. If you develop an allergic reaction to Epsom salts such as hives, edema of your face, diarrhea or upset stomach, stop taking the salts at once and contact your doctor. Using the salts as a soak will relax your muscles and calm your nerves, however, only use the recommended amount and do not exceed what is advised on the label or what your doctor recommends.
Epsom Salts and Spironolactone
Using an Epsom salt soak, even if you are taking spironolactone, is not going to negatively affect your health. However, if you are suffering from kidney disease, cirrhosis or congenital heart failure, ingesting Epsom salts without a dosage that has been carefully determined by your doctor may cause irreparable harm. Too much magnesium in your body, especially if you have kidney disease or renal failure, can be very dangerous, because your kidneys cannot process the excess magnesium quickly enough. Although Epsom salts are used to cleanse your bowels to prepare you for a colonoscopy, your doctor is the one who determines how much and if it is safe to use, depending on your current condition.



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