Turmeric & the Spleen

Turmeric is known for its culinary, cosmetic and commercial uses, but it also contains medicinal properties that help to reduce inflammation and relieve pain. The beneficial effects of this herb are provided by curcumin, its main active ingredient. For centuries, in countries such as China, India and in Southeast Asia, health practitioners have used turmeric for treating problems with the stomach, liver and spleen. But turmeric has proven ineffective against a major disease afflicting a population that uses this herb as a dietary staple.

Myeloproliferative Disorders

Myeloproliferative disorders cause abnormal growth of platelets, white blood cells and red blood cells in bone marrow. When blood cell production occurs in places other than bone marrow, such as the spleen, it causes enlargement of this organ because of inflammation. According to the University of Maryland Medical Center, although herbs have not been studied for myeloproliferative disorders, some herbs provide general health benefits. They suggest taking 300 milligrams of turmeric standardized extract three times a day to alleviate pain and inflammation.

Amyloidosis

Primary amyloidosis, familial amyloidosis and secondary amyloidosis are a group of diseases that can affect any organ or tissue in the body with a build up of a protein known as amyloid. The University of Maryland Medical Center lists diminished function of the spleen as one symptom that might be seen in patients with amyloidosis. Symptoms of secondary amyloidosis can include an enlarged spleen, a condition commonly related to inflammation. Among nutritional supplements that might prevent or mitigate amyloidosis, the University of Maryland Medical Center lists bromelain, an enzyme extracted from the stems of pineapples. Taken with turmeric, which increases its effect, bromelain helps fight inflammation. Bromelain also has a blood-thinning effect that might negatively interact with blood thinners, such as aspirin and Coumadin, also known as warfarin. Consult your doctor before self-medicating with bromelain or turmeric, especially if you take blood-thinning medications.

Negative Effects of Curcumin

According to an article appearing in the September 15, 2008, issue of “Laboratory Investigation,” curcumin interferes with the body’s natural immune response against the parasitic disease leishmaniasis and worsens its infection. Leishmania, which is spread by sandflies, is rampant in India, a country known for its extensive use of turmeric in cooking. The parasite that causes this disease takes up residence in the liver, spleen and bone marrow of humans.

Scientific Evidence

There is minimal reliable scientific evidence to support the efficacy of turmeric for treating health problems in humans. In a 2010 report, “Herbs at a Glance,” the National Center for Complementary and Alternative Medicine, National Institutes of Health, issues a reminder that, while herbs have been used for several thousand years, they can cause reactions and side effects similar to prescription drugs. Taking herbal supplements with other medications can alter their effectiveness. The U.S. Food and Drug Administration regulations for herbal supplements differ from those required for prescription drugs and over-the-counter medications. Because the FDA considers herbal supplements food, federal law does not require proof of safety or effectiveness; it regulates only labeling and health claims. Check with your medical provider before self-medicating with herbs, including turmeric.