1. More Than Just Forgetting Where You Put the Car Keys
A friend's phone number slips your mind, or you forget someone's name. Not usually a cause for alarm, it happens to all of us regardless of our age, but too many of these instances when you're over 70, and chances are you're facing mild cognitive impairment (MCI). Nearly one-third of adults 70 and over are afflicted with this condition, one that does not normally interfere with daily activities. A stage between memory loss due to normal aging and Alzheimer's disease, MCI can affect many cognitive functions, most notably memory, attention, judgment and language. Many cases of MCI have a greater chance of becoming full-blown dementia.
2. Factors of Forgetfulness
More than one factor can play a role in the development of MCI. It may be the result of pre-dementia, where brain cells are being destroyed due to a neurological disorder. Vascular problems that can interfere with the delivery of blood to the brain cells is another physical cause of MCI. Psychological conditions may also lead to MCI, such as depression or mood disorders. A brain trauma or injury might hasten symptoms of MCI. High or low blood pressure, low levels of brain stimulation, diet (most notably high fat intake), education level and genetics may also influence the development of MCI.
3. Link Between Loss of Neuronal Receptor and Loss of Memory
In September 2007, a study by scientists at Emory University School of Medicine and Rush University Medical Center (Chicago) indicated a link between MCI (as well as Alzheimer's) and the loss of a neuronal receptor termed LR11, responsible for binding a protein that carries cholesterol and other fats in the blood. It is also linked to a molecule found in the brain. Both the protein and the molecule are linked to nerve cell degeneration in Alzehimer's patients. The loss of LR11 seems to be a strong indication that one will develop MCI and, possibly later, Alzheimer's.
4. Putting the Brakes on MCI
To date, no treatment plan exists specifically for those with MCI. The use of donezepil, a cholinesterate inhibitor that improves memory function and can delay the onset of Alzheimer's, has been used to treat MCI but is mostly used in those showing mild symptoms of Alzheimer's itself. Nonsteroidal anti-inflammatory drugs (NSAIDs) might reduce inflammation in the brain. Some drugs, such as Piracetam and Hydergine, are used in Europe to treat cognitive impairment, but are not approved in the United States.
5. Aerobics for the Mind
It's long been thought that an active mind is a healthy mind. This adage may hold true when it comes to MCI. Keeping the brain active as we age can play a major role in delaying or preventing the development of MCI as well as dementia and Alzheimer's. Reading, doing crossword puzzles, learning a new hobby, keeping a busy social schedule or taking college courses can all help keep our minds stimulated.
