Glucosamine and chondroitin are common over-the-counter supplements that are used to improve joint pain and function in osteoarthritis. However, the effectiveness of these supplements is still in question. The New England Journal of Medicine reported in 2006 that the combination of glucosamine and chondroitin was not effective in reducing pain in patients with osteoarthritis. However, it may help those with mild to moderate pain. Although these supplements are generally safe and effective, users should be aware of the side effects.
Glucosamine Side Effects
According to Drugs.com, glucosamine is a cellulose-like product that may increase the production of cartilage in joints. Although this supplement is available over the counter, it can have unwanted side effects including constipation, diarrhea, nausea, vomiting, drowsiness, headache and heartburn. If you are experiencing these side effects, alert your doctor.
Chondroitin Side Effects
Chondroitin is a naturally occurring substance that may also enhance the production of cartilage, according to Drugs.com. This herbal supplement is relatively free of known side effects during short-term use, though some people have reported mild stomach upset. There is a lack of research studying the effects of this supplement with long-term use.
Warnings
You should not take these supplements if you are planning to become pregnant, are breastfeeding, or are allergic to glucosamine or chondroitin, according to Drugs.com. Be sure to tell your doctor you are using glucosamine and chondroitin as they may interact with other medications you are taking. Finally, the affect of these supplements on blood sugar levels is not clear, so if you are diabetic, talk to your doctor before using glucosamine and chondroitin.



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