Fluconazole is the generic name for Diflucan, a medication used to treat fungal infections that can affect virtually any area of the body, according to Revolutionhealth.com. These areas include the mouth, lungs, throat, bladder, blood and genital area. It may also be used to prevent fungal infections from occurring in patients who suffer from weak immune systems caused by cancer treatments or AIDS. Effective as it may be, fluconazole may cause a variety of side effects that patients should be aware of.
Commonly Reported Side Effects
Some side effects of fluconazole are considered more common and less severe. They do not generally pose a health risk to the patient and typically subside shortly after taking the prescribed dose. These side effects include digestive problems such as slight nausea, diarrhea, heartburn, vomiting, indigestion and upset stomach, headaches, dizziness, a skin rash and changes in taste which may leave an unpleasant flavor in your mouth.
Reportable Side Effects
Fluconazole may cause side effects that are necessary to report to the doctor. These side effects include an irregular heart beat, flu-like symptoms (such as fever, chills or body aches), a reddened skin rash that is blistering or peeling, unusual weakness, easy bruising or bleeding, and seizures. If you experience these, it is recommended by Drugs.com that you report them to your doctor immediately, as they may be life-threatening.
Liver Damage
Liver damage is another serious side effect of fluconazole, and any signs of it should be reported immediately to the doctor as well. These signs include jaundice; a condition that causes a yellowing of the skin and eyes, urine that is darker than normal and severe upper abdominal pain in the right side. If any of these are experienced, the doctor may perform a routine blood test which may show increased liver enzymes, another indication of liver damage.
Take Heed
Drugs exist that are similar to fluconazole---such as clotrimazole, ketoconazole, tioconazole, econazole, sulconazole and terconazole. Fluconazole is not recommended for patients who are allergic to these drugs, as they may suffer a life-threatening allergic reaction to this medication. Signs of an allergic reaction include swelling of the lips, throat, mouth or face; wheezing or difficulty breathing; hives; or an inexplicable rash and itching. Emergency medical assistance should be sought if these symptoms present themselves.



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