Clorazepate Side Effects

Clorazepate is a medication used to manage anxiety disorders, symptoms of alcohol withdrawal and partial seizures (a type of convulsive disorder). According to Drugs.com, clorazepate is a medication that belongs to the class of drugs called benzodiazepines. Specifically, it balances the neurotransmitters (natural chemicals) in your brain so that you experience a reduced amount of seizures and less anxiety. Typically, your doctor will prescribe 30 mg daily. However, she may increase the dosage to better suit your individual symptoms.

Common Side Effects

According to MedlinePlus, clorazepate can routinely cause dizziness, sleepiness, fatigue, dry mouth and diarrhea. It can cause appetite changes, diarrhea, stomach problems and weakness. Drugs.com indicates that clorazepate can cause trouble sleeping, memory problems, nervousness, muscle weakness and lack of coordination. Inform your physician when these effects do not subside within 4 to 5 days.

Harmful Side Effects

Clorazepate can cause strange behaviors or thoughts, tremors, urinary incontinence and depression, says Drugs.com. Your depression can become very severe and subsequently, lead to suicidal thinking and behavior. Clorazepate's other dangerous side effects include convulsions, trouble breathing, a skin rash, fever, trouble walking, jaundice (yellowing of your skin or eyes) and an arrhythmia (irregular heartbeat). Call your physician right away when you develop these critical effects.

Additional Side Effects

MedlinePlus says that clorazepate can cause constipation, restlessness, frequent urination, changes in your libido (sex drive), impotence and euphoria. It can cause diplopia (double vision), slurred speech and irritability, says the National Library of Medicine.

Miscellaneous Concerns

Do not take clorazepate if you are allergic to it. Facial and throat swelling, difficulty breathing and hives can develop. Call 911.
Do not suddenly discontinue clorazepate. Doing so can lead to such withdrawal symptoms as convulsions, tremors, diarrhea, vomiting, diaphoresis (sweating), muscle cramps and irritability, says the National Library of Medicine. Also, avoid clorazepate if you have a history of drug abuse. Clorazepate is an addicting sedative that can lead to physical and psychological dependence.
Avoid clorazepate if you are pregnant or breastfeeding. The National Library of Medicine says that your baby can develop bodily malformations, especially during the first three months of pregnancy. Clorazepate passes into breast milk and can harm your breastfeeding baby.
MedlinePlus indicates that you should tell your doctor if you are taking the following medications: alprazolam, diazepam, lorazepam or any other benzodiazepine medications. Clorazepate and these drugs do not mix. Combining them may lead to the aforementioned harmful side effects.

References

Article reviewed by Brad Walters Last updated on: Dec 26, 2009

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