Side Effects of Clindesse

Clindesse is a medication made from 2 percent clindamycin phosphate. It is used for the treatment of bacterial vaginosis in women who are not pregnant. It is a convenient one-dose treatment that is highly effective. A back up form of birth control should be used for five days when using this medication, because the mineral oil in Clindesse may cause damage to the latex in condoms and diaphragms. In a survey of 20,000 women conducted by the manufacturer, 97 percent said they would use Clindesse again. During clinical trials, 1.6 percent of patients stopped treatment due to reported side effects. The most frequently reported side effects were fungal vaginosis (14.1 percent), vulvovaginal itching (3.3 percent) and headache (2.7 percent).

Fungal Vaginosis

In women using Clindesse for bacterial vaginosis, there is an increased risk of developing fungal vaginosis. Consider seeing your practitioner if the symptoms do not subside within one week of initiating treatment. Symptoms of fungal vaginosis include burning, soreness, pain during intercourse and a thick whitish discharge.

Vulvovaginal Itching

Vulvovaginal itching is an itching of the vagina and surrounding area of the vulva. This may occur while using Clindesse. Being that this is a one-time treatment, if you experience this side effect, wash the affected area and keep it dry. If it does not subside, see your practitioner, who may be able to prescribe you a cream to alleviate the itching that you are experiencing.

Headache

A small percentage of women reported a headache while using this drug. In the even that you experience headache, you can treat it with either acetaminophen or ibuprofen. If the headache does not subside or continues to worsen, contact your provider.

References

Article reviewed by Roman Tsivkin Last updated on: Dec 29, 2009

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