Lodine XL is the brand name for an extended release pill generically called etodolac. It is a non-steroidal anti-inflammatory drug (NSAID). Lodine XL is prescribed in the treatment of both rheumatoid arthritis and osteoarthritis, and helps lessen the symptoms of these diseases. Specifically, it can help with pain in the joints, bodily stiffness, swelling and inflammation, according to the Mayo Clinic.
Serious Side Effects
Lodine XL may induce a variety of serious side effects. These are relatively common, according to the Mayo Clinic, and require an immediate talk with your physician. They may include cramps or pain in the stomach, chest pain, belching, tar-like stools that may contain blood, nervousness, vision blurring, vomiting and nausea, aches throughout the body, pain in your side or lower back, cloudy urine, appetite loss, nasal congestion and itching. Others may be constipation, bradycardia (slow heartbeat) or tachycardia (fast heartbeat), cough, reduced urination, bodily swelling, diarrhea, severe stomach pain, dizziness, runny nose, sore or dry throat, indigestion, rash or fever. Other possibilities for serious side effects include loss of weight, headaches, vomiting blood, changes in voice, skin paleness, breathing or swallowing problems, and abnormal weakness, tiredness, bruising or bleeding.
Temporary Side Effects
There are a few side effects that should be temporary. These include a stuffy nose, bloating, sneezing, noises in the ears that sound like buzzing or ringing that are continual, flatulence, loss of hearing and decreased strength. While these probably will go away as you acclimate to Lodine XL, if they don't, tell your doctor about them.
Overdose Side Effects
A dose of Lodine XL can be anywhere from 400 to 1,000mg once per day, depending on your doctor's orders. Taking more than recommended can cause an overdose with associated side effects. Contact your doctor about any of these if you have exceeded the prescribed dose: abnormal drowsiness or sluggishness, agitation, consciousness changes, chest tightness, mental confusion, facial swelling, depression, swelling of the hands or ankles, breathing difficulties (including shortness of breath), hives, stupor and hostility toward people. Others may include rapid weight gain, irritability, muscle twitching and unconsciousness.
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