Side Effects of Chlordinium

Chlordinium (chlordiazepoxide and clinidium bromide) is a medication used to manage irritable bowel syndrome and stomach or intestinal ulcers. According to Drugs.com, Chlordinium is a benzodiazepine that reduces stomach acid production and intestinal spasms. Typically, you take one to two capsules three to four times a day, says the National Library of Medicine.

Common Side Effects

According to MedlinePlus, Chlordium's most common effects include heartburn, trouble sleeping and photosensitivity. Heartburn, also known as acid reflux, refers to a condition in which your stomach acid backs up in your esophagus and into your mouth. This results in chest pain and can leave an extremely sour test in your mouth. Simply taking over-the-counter antacids can neutralize stomach acid. Photosensitivity refers to a medical condition in which your skin is extremely sensitive to sun exposure. Wear sunblock with a sun protection factor (SPF) of at least a 15 to protect skin from the sun's potentially damaging ultraviolet rays. Chlordinium can also cause dry mouth, constipation, blurry vision, changes in sense of taste and changes in appetite. Call your doctor when any of these symptoms do not resolve within three to four days.

Serious Side Effects

Drugs.com says that Chlordinium can cause jaundice (yellowing of skin or the white parts of your eyes) and infrequent urination. Jaundice is an indication of liver destruction; decreased urination can lead to acute kidney failure. See your doctor right away. He'll get a blood and urine sample. He will check your blood for elevated liver enzymes and increased blood urea nitrogen (BUN) levels (a substance that measures kidney function). Elevations in these natural substances are indicative of the aforementioned side effects. Chlordinium can also cause changes in mental state. It can cause hallucinations, confusion, depression, agitation, hostility and suicidal thoughts. It can also lead to involuntary movements of your tongue, jaw and neck. Inform your physician immediately when Chlordinium causes these symptoms.

Additional Concerns

Avoid Chlordinium if you're allergic to chlordiazepoxide, clidinium bromide or any other benzodiazepine medications. An allergic reaction consists of such manifestations as skin welts throughout your body, swelling of your throat and difficulty breathing. Call 911.
Do not drink alcohol while taking Chlordinium. The combination of Chlordinium and alcohol can lead to the aforementioned effects.
According to the National Library of Medicine, Chlordinium can cause birth defects, especially during the first three months of pregnancy. Tell your doctor if you are pregnant.
Avoid abruptly stopping Chlordinium. This can lead to such withdrawal symptoms as vomiting, convulsions, tremors, vomiting and stomach pain, says the National Library of Medicine.
Drugs.com indicates that you should not use this medication if you have glaucoma, an enlarged prostate gland, kidney problems, asthma, a history of suicidal thoughts or behavior or a history of drug and alcohol abuse. Chlordinium can become physically and mentally addictive.
Do not take Chlordinium while taking such medicines as amobarbital and warfarin; monoamine oxidase inhibitors such as phenilzine; narcotic medicines such as morphine; and antidepressants such as fluoxetine.

References

Article reviewed by Anton Alden Last updated on: Jan 2, 2010

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