Amlodipine (brand name Norvasc) is a commonly prescribed calcium channel blocker for high blood pressure. Amlodipine works by inhibiting calcium ions from entering vascular smooth muscle cells (found in blood vessels), thus vasodilating, or relaxing, the blood vessels. This vasodilation allows for more blood and oxygen to reach the heart, and a healthy supply of blood and oxygen to the heart is critical to maintaining and controlling blood pressure. Amlodipine is taken once daily by mouth as a tablet or disintegrating tablet, and is available by prescription only. Norvasc.com recommends consulting with your health care provider prior to starting or stopping another medication regimen, including other medications for high blood pressure.
Common Side Effects
Some possible common side effects, as reported by MedlinePlus, include dizziness, stomach pain, upset stomach, headache, drowsiness, swelling of the ankles, feet, hands or lower legs, excessive tiredness and flushing (warmth or redness under the skin). Drugs.com also notes that some patients may have difficulty sleeping while taking amlodipine, and may have strange dreams. Some may also experience mild skin rash, itching, joint or muscle pain, weight changes, increased frequency of urination, dry mouth, increased sweating, thirst, loss of appetite, nausea and vomiting.
Serious Side Effects
Serious side effects are generally uncommon; however, do not hesitate to report such effects immediately to your medical care provider. You may also report side effects to the Food and Drug Administration (FDA) at (800) 332-1088. MedlinePlus lists pounding, rapid or irregular heartbeat, fainting, and frequent or severe chest pain as serious side effects. Drugs.com notes other serious side effects such as as jaundice (yellowing of the eyes or skin), numbness, burning pain or tingly sensation, easy bruising or bleeding, and weakness. Some may also experience a severe allergic reaction to this medication. Symptoms of an allergic reaction include difficulty breathing, hives, and swelling of the throat, hands, face, lips or tongue.
Considerations
Elderly people may have increased sensitivity to the effects of amlodipine; thus side effects of this medication may substantiate as more severe. MedlinePlus recommends keeping a list of all over-the-counter (nonprescription) medications, dietary supplements (vitamins, minerals, herbs) and prescription medications you are currently taking. Keep this list with you and be sure to bring it to any doctors' appointments or hospital visits.
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