Zyban (buproprion) is a medication used to reduce your nicotine cravings. It is also used to treat major depressive disorder and seasonal affective disorder (depression that occurs with seasonal changes). According to MedlinePlus, Zyban is an antidepressant medication that alters your neurotransmitter (brain chemical) levels. Typically, you will take 150 mg of Zyban twice a day.
Common Side Effects
In a placebo-controlled study of 461 patients taking 100 to 300 mg of Zyban, the National Library of Medicine says that 2 percent experienced neck pain, 1 percent developed hot flashes and hypertension (high blood pressure), 11 percent developed dry mouth and 2 percent developed an increased appetite. Also, 4 percent developed arthralgia (joint pain), 2 percent developed myalgia (muscle pain), 31 percent experienced trouble sleeping, 8 percent experienced dizziness, 2 percent experienced tremors and bronchitis. Additionally, 3 percent developed a skin rash and itching and 2 percent developed dry skin and alterations in taste sensation.
Serious Side Effects
The National Library of Medicine indicates that Zyban can increase your chances of developing serious psychiatric disturbances. You can develop depression and suicidal thinking and behaviors. Discontinue Zyban and tell your physician if you develop these symptoms. Also, Zyban can cause agitation, hostility, aggression and panic episodes. It can also increase your risk for seizures. The National Library of Medicine says that doses greater than 300 mg daily are not recommended as this can provoke seizures. MedlinePlus indicates that Zyban can also cause chest pain, trouble breathing, hoarseness, hallucinations, confusion and swelling of your arms, legs and ankles. Phone your doctor when Zyban causes these effects.
Additional Concerns
Avoid Zyban if you are allergic to buproprion. A hypersensitivity response to buproprion includes such side effects as trouble breathing, hives and throat, tongue or facial swelling. Do not combine Zyban with monoamine oxidase inhibitors such as phenilzine, rasagaline or selegiline, says Drugs.com. The combination of Zyban with these medications can cause the aforementioned side effects. Avoid Zyban if you have epilepsy (a seizure disorder), an eating disorder or have heart or kidney disease. Zyban may exacerbate these conditions.
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