Side Effects of Effexor-XR Medicine

Effexor (venlafaxine) is used to treat depression and certain anxiety disorders (including panic disorder). Effexor-XR is the extended release version of this medication. It can take up to four weeks or more before you feel the full effect of Effexor-XR, and you may need to take the medication for at least six months, even if you feel better. Consult your doctor prior to stopping this medication.

Common Side Effects

Certain side effects of Effexor-XR are common and may not necessarily require medical attention. The Mayo Clinic reports that these include abnormal dreams, anxiety, dry mouth, increased sweating, stuffy or runny nose, weakness, weight loss and trembling. Digestive issues such as constipation, diarrhea, heartburn, loss of appetite, nausea, stomach pain, vomiting or gas are common. RxList.com also notes that Effexor-XR may increase blood pressure, so your blood pressure should be closely monitored while taking this medication. If any of these side effects are persistent or severe, contact your doctor.

Serious Side Effects

Some side effects are not common, but may be serious if they occur. These include fainting, severe headache, severe mood changes, shakiness, decreased interest in sex, changes in ability to perform sexually, difficulty urinating or changes in volume of urine. Other serious side effects include stomach or chest pain, irregular heartbeat, muscle weakness, yellowing of the eyes or skin, dark urine, seizures, unusual fatigue, bloody/black/tarry stools, vomit that looks like coffee grounds, easy bleeding or bruising, or persistent cough. The National Library of Medicine (NLM) reports that other serious side effects include hallucinations, small purple spots on the skin, changes in vision or coma (loss of consciousness).

Serotonin Syndrome

Antidepressants rarely cause a very serious condition called serotonin syndrome. Your risk for this syndrome increases if take this medication with certain other medications. According to RxList.com, symptoms of serotonin syndrome include hallucinations, fast heartbeat, restlessness, loss of coordination, severe dizziness, unexplained fever, twitchy muscles, or severe digestive issues such as nausea, vomiting or diarrhea.

Warning

RxList.com warns that antidepressants may increase the risk of suicidal behavior and thinking in children, adolescents and young adults during the first few months of treatment. If you notice any suicidal thoughts or behaviors, immediately contact a medical professional or emergency services.

References

Article reviewed by Roman Tsivkin Last updated on: Jan 5, 2010

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