The vaginal cream Premarin contains estrogen hormones. Drugs.com indicates that it is used to treat the symptoms of menopause, such as hot flashes and vaginal dryness, burning or irritation. Other uses of the cream include preventing osteoporosis and the regulation of estrogen levels in postmenopausal women. Estrogen is a hormone produced in women by the ovaries and is necessary for many processes in the body. There is a risk of side effects with the use of Premarin topical cream.
Most Common Effects
Premarin cream use can lead to several common effects often considered to be mild, states eMedTV.com. Such effects may diminish with continued use of the medication, but discuss any persistent effects with your doctor. The most common effects are headaches, abdominal pain, pain in the back or joints, unusual vaginal bleeding, accidental injury or pain in the breasts. Pain medication can be used to reduce these side effects.
Common Side Effects
Less common effects that impact between five and 10 percent of cases, as indicated by eMedTV.com, include weakness, gas, leg cramping and/or nervousness. Women using Premarin have an increased risk of yeast infection, irritation or a milky white discharge. Drugs.com lists other common effects like back pain, bloating, depression, diarrhea, dizziness, flu-like symptoms, hair loss, indigestion or upper respiratory tract infection. These are considered to be mild unless they become persistent or overly bothersome, reports Drugs.com.
Stroke
There are several serious hazards associated with the use of Premarin topical cream, including the risk of a stroke. Signs of a stroke include changes in speech of vision, weakening or numbing of the extremities, or the sudden onset of a severe headache, according to eMedTV.com
Liver Damage
Liver damage can be recognized by the yellowing of the skin or the eyes (jaundice), darkened urine or pain in the upper right section of the stomach. Migraine headaches may appear or change in severity with the use of Premarin.
Lumps or Clots
Premarin topical cream can increase the risk of blood clots in the legs, lungs or the eyes. According to eMedTV.com, signs of this include pain in the calf, leg cramping, swelling of the foot or leg, shortness of breath, sharp chest pain, coughing up blood, or a sudden loss of vision or changes in sight.
Other Side Effects
The breasts can develop lumps that may or may not be benign, reports Drugs.com. Serious vaginal problems include heavy or unexpected bleeding. Sexual intercourse may be painful, or a woman's libido may be diminished with the use of Premarin cream. Unusual vaginal odor should be reported to a doctor for follow up.
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