Pseudoephedrine is a decongestant drug frequently found in many over-the-counter medications for the temporary relief of cold, flu or allergy symptoms, specifically, nasal, sinus or eustachian (inner ear) tube congestion. According to Flexyx.com, it is a sympathomimetic drug; that is, it reduces swelling by shrinking dilated blood vessels, which results in reduced congestion. Typically, this decongestant is not considered to be dangerous if taken as recommended; however the potential for side effects is always present.
Nervousness
This drug can produce several common and mild effects. As a stimulant, pseudoephedrine may produce symptoms such as increased nervousness or anxiety in some individuals, as well as tremors or shakiness. This arousal side effect may also be displayed as restlessness and insomnia. Because this drug is associated with stimulating effects, individuals highly sensitive to substances such as, for example, caffeine, should avoid products and beverages that contain caffeine while taking this medication.
Stomach Upset
Pseudoephedrine has been known to irritate the stomach. It may produce feelings of nausea or an upset stomach, which may or may not be accompanied with actual vomiting. Other possible side effects of this drug on the gastrointestinal system include a dry mouth and a decrease in appetite. In rare cases, diarrhea may occur. While on this medicine, taking it with a glass of water may help reduce of the stomach upset. However, if side effects continue, a physician should be notified.
Headaches
In addition to the above, less common side effects may present. These may include headaches, dizziness or feeling lightheaded. Initially, lying down may alleviate these side effects if they occur. However, a doctor should be contacted if they persist or become worrisome.
Cardiac
More serious heart-related side effects have been documented with this medication. Some examples that may occur include irregular heartbeats, pounding and rapid heartbeats (tachycardia), increased sweating as well as chest discomfort. Additionally, changes in blood pressure may be experienced. Some of these effects have been found to occur in cases in which an individual has a medical history of cardiovascular disease such as hypertension prior to taking this medication. Therefore, it is important to provide your doctor with a complete medical history and a list of current medications because pseudoephedrine may interact with some of these medicines, which include beta-blockers, high blood pressure medications and certain antidepressants.
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