Long-Term Effects of Lyrica

Lyrica (pregabalin) is an antiepileptic drug approved by the Food and Drug Administration in 2004. It's prescribed for several conditions, including nerve pain in diabetics (diabetic peripheral neuropathy), fibromyalgia, partial seizures (seizures affecting only part of the brain) and postherpetic neuralgia (nerve pain following a case of shingles).

Depression/Suicidal Thoughts

Antiepileptic drugs such as Lyrica have been associated with new or more severe symptoms of depression, including suicidal thoughts and behavior. Although these symptoms usually appear early, they have the potential to worsen over time. Report any such thoughts or behaviors to your doctor immediately.

Weight Gain

According to the FDA, Lyrica has been associated with an increased risk of weight gain, particularly in patients who also take some types of diabetes medications. This side effect may cause serious problems for diabetics or those with heart conditions. Before taking Lyrica, inform your doctor if you are diabetic or suffer from any heart problems.

Bleeding

Lyrica has been associated with a decreased platelet count in some patients.This can lead to an increased risk of bleeding or bleeding incidents. If you have any bleeding problems, tell your doctor before taking Lyrica.

Other Side Effects

Other side effects associated with taking Lyrica may include swelling of the face, lips, tongue, or throat, which may cause trouble with breathing, dizziness or blurred vision, muscle pain or weakness, and trouble concentrating. Before taking Lyrica, discuss with your doctor any health problems you have and all medications you're taking.

References

Article reviewed by Anton Alden Last updated on: Jan 14, 2010

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