Augmentin Side Effects

Augmentin is an antibiotic based on the prototype ampicillin. A combination of amoxicillin and clavulanate potassium, Augmentin is effective against haemophilus influenzae, staphylococcus aureus, and Streptococcus pneumoniae. These organisms are responsible for many types of upper-respiratory tract infections, acute bacterial sinusitis, community-acquired pneumonia and otitis media (middle ear infections). Augmentin can cause side effects.

Hypersensitivity Reactions

Augmentin is classed as a penicillin, so any person allergic to penicillin should not take the drug. People with a history of a hypersensitivity reaction (allergic reactions) to cephalosporin drugs should use caution when taking Augmentin because a similar sensitivity response is possible.
Hypersensitivity reactions to Augmentin include a generalized itchy rash, which typically develops a couple of days after starting the medication, and possibly fever and wheezing. Symptoms could be mild to severe and any of these symptoms should be reported to a physician immediately.
Ampicillin is known for causing a generalized erythematous (red ) raised rash; because Augmentin is related to Ampicillin, this adverse reaction may also occur. This rash is normally mild and not caused by a hypersensitivity reaction. However, until a hypersensitivity reaction can be ruled out, the symptoms should be reported to a physician.

General Adverse Reactions

Augmentin commonly causes an upset stomach. Nausea and vomiting may occur. To minimize these adverse reactions, take Augmentin with food. Taking Augmentin with food aids in absorption of the medication and also decreases gastrointestinal symptoms.
Augmentin, like many antibiotics, may cause diarrhea. Eating plain yogurt with live and active culture on a daily basis while taking Augmentin may help alleviate this common side effect. Notify your physician if symptoms continue for two or more days or are severe, because a serious secondary infection by clostridium difficile may occur.
Women taking Augmentin are at risk for developing vaginal yeast infections. Symptoms of thick, non-odorous vaginal discharge, vaginal inflammation and itching should be reported to a healthcare provider.

Toxic Effects

Augmentin has the potential to cause organ toxicity; the kidneys, liver and the hematopoietic system (blood cell production) may each be affected. The National Institute of Health (NIH) advises that patients with a history of renal or hepatic impairment should not use, or should use caution, when taking Augmentin. The NIH advises that baseline lab values to assess kidney, liver and hematopoietic function should be conducted at the beginning of therapy. The longer the therapy, the greater the risk of toxicity.