Doryx is a time-release form of an antibiotic prescribed to treat various bacterial infections, including acne. It contains doxycycline hyclate, a type of tetracycline, and is available in tablets of 75, 100 and 150mg. This medicine can be effective for acne treatment, but patients should be aware of possible side effects. Doryx is more expensive than generic doxycycline, but has certain advantages over the generic drug.
Function
Doryx reduces bacterial colonies and also has anti-inflammatory properties. Doctors sometimes prescribe Doryx when acne does not improve with topical treatment. The oral antibiotic may be used on its own or in addition to topical antibiotic or topical retinoid therapy. Doctors also prescribe Doryx as beginning therapy for severe acne.
Doryx Advantages
Doxycycline commonly causes stomach upset. Because of the time-release action, Doryx does not begin working until it reaches the small intestine, and this decreases or prevents gastrointestinal side effects. Patients also are less likely to miss a dose because they only need to take Doryx once a day, unlike other forms of the medicine.
Usage
Doryx use for acne typically begins with 200mg the first day, according to Physicians' Desktop Reference, taken in two separate 100mg doses. The patient then takes 100mg once per day thereafter. You may not see improvement in your acne for up to four weeks.
Interactions and Side Effects
Doryx can reduce the effectiveness of antacids, blood thinners, oral contraceptives and vitamins. Additionally, iron supplements and milk can reduce the effectiveness of Doryx. Doryx causes photosensitivity, leading to severe sunburn if you spend time in the sun without adequate clothing or sunblock. Other side effects are unlikely and should be reported to a doctor immediately. These side effects include fever, pain when swallowing, nausea, stomach pain, weakness, fatigue and unusual bruising. Signs of an allergic reaction include a rash or hives, facial swelling and difficulty breathing.
Warning
Serious and sometimes life-threatening cases of colitis are associated with the use of Doryx and other antibiotics because they kill friendly intestinal bacteria. Anyone experiencing even mild diarrhea while taking Doryx or for several weeks after discontinuing it should seek medical attention. The medicine can cause permanent tooth discoloration while teeth are developing, so young children should not take Doryx. Pregnant women also should not take Doryx because it can cause birth defects. Expired Doryx can cause kidney damage.
