As you continue to age, it is the natural course of your body to start breaking down fat as well as important proteins in your skin tissue called elastin and collagen, two important substances that give skin its elasticity as well as its volume. As these proteins break down, the skin tissue gets thinner causing the skin to droop and wrinkle. This process can be accelerated by disease, the environment and overexposure to ultra-violet radiation from the sun. To combat the loss of these proteins, many people choose to use dermafillers (wrinkle fillers), which are products used to replace space under the skin lost to the break down of proteins.
Collagen
Collagen injections are one of the most common wrinkle fillers on the market. Collagen can come from both human sources (CosmoDerm and CosmoPlast) or bovine-based sources (such as ZyDerm and ZyPlast). Before injecting the bovine-based collagen, your physician may administer an allergy test to ensure that you are not allergic to the treatment. Human-based sources of collagen do not require this allergy test.
Fat
Fat injections can also be used as a dermafiller for wrinkles on your body. Fat dermafiller usea donor fat from other areas of your body, such as from your abdomen or thighs, and transplant the fat to below wrinkles. This plumps out the wrinkle to be even with the surrounding tissue.
Hyaluronic Acid
Hyaluronic acid can also be used as an injectable dermafiller for wrinkles. Hyaluronic acid is one of the most popular ingredients for dermafillers with its presence being in several brands, such as Juvederm, Dermalive, HylaForm, Captique and Restylane. Hyaluronic acid works by filling in the lost space between elastin and collagen fibers, restoring skin to its original volume.
Poly-L-lactic Acid
Poly-L-lactic acid, sold on the market as Sculptra, is also a common injectable dermafiller. Poly-L-lactic acid is used to replace fat lost with aging. Poly-L-lactic acid is a synthetic product that is also used in dissolvable body screws and stitches, making it biodegradable in the body.



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