Diovan (valsartan) was one of the first angiotensin II receptor blocker (ARB) drugs marketed for the treatment of high blood pressure by Novartis in 1996. According to the Joint National Committee on Prevention, Detection, Evaluation, and Treatment of High Blood Pressure, ARBs should be first or second line choices for the treatment of high blood pressure. Reports in the journals Diabetes Care and The New England Journal of Medicine indicate Diovan may also protect the kidneys of diabetic patients and increase the lifespan of patients with heart failure.
Side Effects
According to the American Family Physician, dizziness may occur in 2 to 4 percent of patients and can be related to a first-dose effect (blood pressure lowers inappropriately after initially starting the medication). For this reason, Diovan is started at a low dose and gradually increased. A dry cough can be expected in up to 3 percent of Diovan users. Diarrhea, joint aches (arthralgias), low back pain, headache and fatigue can infrequently occur in patients taking Diovan.
Hyperkalemia
Hyperkalemia (elevated levels of potassium in the blood) can occur in patients taking Diovan and is more likely in older patients with diabetes, kidney disease and heart failure. Many drugs, including nonsteroidal anti-inflammatory drugs like ibuprofen, as well as potassium and herbal supplements, can also affect the blood potassium level when taken along with Diovan.
Angioedema
Angioedema, characterized by swelling of the face and around the eyes, nose and lips, is an extremely rare complication that may occur hours, days or even weeks after starting Diovan. This can be life-threatening if the tongue and/or airway are involved and requires immediate medical attention.
Member Comments