Cymbalta Side Effects on Fibromyalgia

Cymbalta (duloxetine) is an antidepressant approved by the FDA to treat fibromyalgia. Fibromyalgia is a collection of symptoms without an identifiable cause. Symptoms of the condition include depression, headaches and pain over specific areas of the body. The side effects of Cymbalta include gastrointestinal problems, fatigue and depression. Paradoxically, these are some of the same symptoms of the disease in question. Cymbalta may cause, mimic or aggravate symptoms similar to fibromyalgia; however, these symptoms can gradually diminish or dissipate over time and actually bring the illness under better control.

Gastrointestinal Symptoms

Side effects of Cymbalta to the gastrointestinal system can include nausea, dry mouth, decreased appetite, stomachaches and pain, diarrhea and constipation. The website Rxlist.com reported 19.5 percent of patients given Cymbalta on a study trial experienced adverse effects of the drug, which included nausea, fatigue and sleep disturbance. These symptoms may gradually disappear or dissipate over time and actually improve when first starting Cymbalta. Keeping a journal or a daily diary of symptoms may help you monitor your progress. In addition, taking medication with food may help reduce or alleviate gastrointestinal problems.

Sleepiness and Anxiety

Common symptoms of fibromyalgia are fatigue, anxiety, poor-quality sleep and sleepiness. Sleepiness is also a common side effect of Cymbalta, according to a February 2010 New York Times article. The symptoms of fibromyalgia can be exaggerated when first taking Cymbalta because the drug can exacerbate and make them worse. If symptoms worsen or don't improve, patients must inform their doctor.

Depression

Depression can also be aggravated by the use of Cymbalta. The website Rxlist.com reported that this drug can worsen depression and increase the suicide risk in patients.As depression and its actions can be serious and life-threatening, a user of this drug must always consult his physician if signs of depression appear or worsen.

References

Article reviewed by Matt Olberding Last updated on: Feb 4, 2010

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