What Is Propo-N/APAP Tab?

Propo-N/APAP tab is the generic name for a prescription medication containing propoxyphene napsylate and acetaminophen. Common formulations of this medicine contain 100 mg of propoxyphene napsylate and 650 mg of acetaminophen. This drug is a controlled substance and is often prescribed as one tablet every four hours as needed for pain relief.

Propoxyphene Napsylate

Propoxyphene napsylate is an opioid agonist analgesic, meaning that it works in certain areas of the central nervous system to produce pain relief. It is also responsible for a "high" feeling called euphoria, and sedation. Propoxyphene is indicated for the relief of mild to moderate pain.

Acetaminophen

According to one major manufacturer of acetaminophen, this compound is believed to work by raising your threshold for pain. It is indicated for the relief of mild pain. Acetaminophen can cause serious liver problems when taken frequently or for a long period of time.

Side Effects

Common side effects of propoxyphene napsylate with acetaminophen include nausea, vomiting, extreme tiredness and dizziness. Less common side effects include chest pain, headache, constipation, stomach pain, low blood sugar, altered mood, feeling "high," weakness, difficulty breathing, fever, rash, yellowed skin, bluish skin, blood in the urine, lack of urine, kidney damage, kidney failure, liver damage and liver failure. Lowered levels of white blood cells, red blood cells and platelets may also occur.

Tolerance, Dependence and Abuse

Tolerance can develop when taking this drug for an extended period of time, meaning that a larger dose of the same medicine becomes required to relieve the same degree of pain after long-term use. This can become a serious problem as a higher dose may not be safe due to the side effects of both of the active ingredients. It is possible to become dependent on this medicine and require professional assistance to stop taking it. As with all controlled substances, propoxyphene napsylate with acetaminophen has the potential for abuse, whether obtained by prescription or illegal diversion.

Considerations

This medication should be taken as prescribed and only for as long as it is needed for pain. Do not take other products containing acetaminophen, including some over-the-counter pain relievers, sleep aids and cold remedies, while taking this product. According to "2010 Lippincott's Nursing Drug Guide," you should not consume alcohol while taking this drug. If this medication makes you sleepy, dizzy or have trouble seeing correctly, do not perform critical tasks such as driving. People who are known to be susceptible to addiction or who have suicidal thoughts should not take this medicine.