Acne is common skin condition that typically results in clogged pores, pimples, blackheads and whiteheads. As many as 45 million people in the United States suffer from acne, according to the University of Maryland Medical Center. There are a number topical acne remedies. One of the most tried and true prescription-only acne medications is tretinoin, which is found in brand name medications such as Retin-A, Retin-A Micro, Renova, Refissa, Tretin-X, Atralin and Avita.
Effects
The American Academy of Dermatology says tretinoin was the first retinoid developed for topical use. Retinoids are derivatives of vitamin A that help prevent skin pores from becoming blocked. This helps stop the formation of whiteheads and blackheads. Tretinoin discourages acne from developing by rapidly removing old skin cells. Tretinoin also works to reduce roughness and improve the overall texture of the skin.
Considerations
When you first begin using tretinoin, don't be alarmed if your condition seems to flare up. Tretinoin is simply bringing acne that is deeply lodged in the skin to the surface to help clear it out of your system. It can take several weeks to notice any improvement.
Application
Gently wash your skin with a mild cleanser using the tips of your fingers and pat dry. Wait until your skin has thoroughly dried (20 to 30 minutes) before applying tretinoin cream. Your skin may become irritated if you rub the medication onto wet skin. Spread a pea-sized amount of tretinoin cream over the affected areas of your skin.
Dosing
Tretinoin cream is available in strengths ranging from 0.02 to 0.1 percent. Your dermatologist will determine which potency is best for your acne condition. Make sure you follow the dosing directions. If you happen to miss a dose, don't use twice as much cream in an an attempt to make up for the lost treatment. Skip the missed dose and resume your regular treatment schedule.
Side Effects
A number of side effects are possible with tretinion, especially at the onset of treatment as your skin adjusts to the medication. You may experience redness, dryness, a mild warm sensation, stinging or tingling of the skin. In rare cases skin discoloration has occurred, but it typically returns to normal within a few months.



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