Tretinoin cream is a medication with more than just one purpose. Although tretinoin is more commonly associated with acne treatment, it's also approved by the U.S. Food & Drug Administration to reduce the effects of photoaging on the skin (wrinkles). Although effective, tretinoin cream has harsh, unappealing side effects. If you use tretinoin cream for wrinkles, it's necessary to follow your dermatologist's instructions, as well as avoid sun exposure and cold, windy weather.
About Tretinoin
Tretinoin, a natural derivative of vitamin A, falls under a broader category of topical drugs called retinoids, according to the American Academy of Dermatology. The most commonly recognized trade name the drug tretinoin goes by is Retin-A, but it's also sold under the names of Altinac, Avita, Renova, Tretin-X and other brand names, according to Drugs.Com. In addition to cream, tretinoin is available as a gel. Tretinoin is available in a variety of strengths measured by the amount of tretinoin per gram, including 0.1, 0.05 and 0.025 percent.
What It Does
In wrinkled skin that's a result of intrinsic or extrinsic aging (photoaging), dead skin cells don't turn over as quickly as they do in more youthful, unweathered skin. Tretinoin increases the rate of dead cell turnover as well as the formation of new skin cells. Not only does it eradicate minor wrinkles, it can also reduce rough patches on the skin as well as irregular pigmentation, according to the Mayo Clinic.
How It's Used
Tretinoin cream is applied to skin that's been washed with a mild soap, about 20 to 30 minutes after it has been blotted dry. Usually, no more than a pea-sized amount of the medication is needed to cover the entire face, according to the Mayo Clinic. Using more of this medication won't make it work any better and will increase the side effects. It's important to avoid getting tretinoin cream on sensitive parts of the face--the lips, inside of the nose or close to the eyes. It shouldn't be applied to skin that's sunburned, windburned or that has open sores.
Side-Effects
Common side effects of tretinoin cream during the first few weeks of use include mild redness, slight peeling, dryness and burning, which often subside once you've adapted to using the medication. However, if any of these symptoms are severe, or if you notice that your skin has lightened or darkened, contact your health-care provider for advice.
Other Precautions
Tretinoin cream makes the skin more sensitive to the sun and harsh weather. Mayo Clinic experts note that staying out of the sun is recommended, and this includes avoiding UV rays from tanning beds and sun lamps. Always apply sunscreen with a sun protection factor of at least 15 before going outdoors and wear a wide-brimmed hat for extra protection. Also avoid going outside whenever it's cold and windy.



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