Cymbalta, or generically duloxetine, is an antidepressant medication that also may be prescribed for generalized anxiety disorder or to help people cope with the pain of severe nerve damage associated with diabetes. It also may be used in the treatment of fibromyalgia, which produces stiffness and pain in the muscles. Cymbalta is an SSNRI (selective serotonin and norepinephrine reuptake inhibitor) that helps improve norepinephrine and serotonin activity in the brain. It is administered as a capsule.
Pain
Cymbalta fairly commonly leads to some pain, drugs.com states, but the pain will go away in most people as the antidepressant therapy continues. These effects do not require medical treatment unless they persist. The patient may experience pain in various locations throughout the body, headaches, muscle aches and throat soreness.
Sexual Effects
There are two potential sexual side effects categorized as common, according to drugs.com, that are also temporary and not serious. The first is a lowered libido, meaning interest in having sexual intercourse or participating in other sexual activity, as treatment with Cymbalta begins. The second is a decrease in sexual performance or drive. While these effects can be frustrating and disconcerting, they should disappear with regular use of the drug. Patients should call a physician if these effects persist past the beginning of treatment.
Bowel and Stomach Effects
Cymbalta also may induce problems with bowel movements as treatment begins. These are common side effects not considered serious unless they continue. Constipation and difficulty passing a bowel movement can occur, or conversely the patient may have loose stools and diarrhea. Bowel problems may or may not be accompanied by other common, nonserious side effects such as appetite loss, nausea and vomiting.
Other Side Effects
According to the National Institutes of Health, some other common and temporary side effects are associated with taking Cymbalta. Patients may experience increased sweating or night sweats--unexplained extreme perspiration that soaks clothing and the bed. There also is the potential of bodily weakness and uncontrollable shaking in parts of the body. None of these effects are considered serious.
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