Drug Side Effects Of Plavix

According to Mosby's 2010 Nursing Drug Reference book, Plavix, or clopidogrel bisulfate, functions as a platelet inhibitor for people at high risk for blood clots as a result of stroke, myocardial infarction or who have a history of peripheral arterial disease, unstable angina or coronary artery bypass grafts. Patients on a regimen of Plavix carry a risk for bleeding disorders and drug interaction dangers with both prescribed and over-the-counter medications.

Gastrointestinal Side Effects

The most common and serious gastrointestinal side effect from Plavix therapy is a risk of hemorrhage. Dark, tarry stools are an indicator that there may be blood in the GI tract. Such symptoms should be reported to your doctor immediately. Usually a reduction in the drug's dosage will alleviate these symptoms. Constipation, diarrhea and ulcers are other less serious side effects that may be treated with symptom management remedies available from your physician.

Hematologic and Integumentary Side Effects

Small, red dots called purpura may surface on the skin in the patient taking Plavix. The purpura themselves are not painful unless the condition becomes severe and the purpura inflamed. A condition called pruritus is an itchy, oftentimes burning rash on the surface of the skin which may occur when the platelet count falls below normal levels, and the skin is no longer an effective retainer of blood products. Any rash should be reported to the doctor to determine whether an allergy to the medication exists or the drug dosage needs an adjustment. Patients should note that clotting time for small cuts and scrapes may be prolonged when taking Plavix. Patients may notice they are more susceptible to bruising.

Central Nervous System Side Effects

Plavix's anti-platelet actions may cause dizziness, fatigue and headaches. Rising too fast from a sitting or reclining position, bending over, and exercise may cause a person to feel light-headed when on Plavix. Care should be taken to prevent falls and syncope in a person on anti-platelet therapy. Aspirin taken for a headache and other blood-thinning medications may increase the side effects of Plavix. A patient should consult a doctor before taking these drugs while on Plavix.