Pseudogout
Pseudogout, as Medline explains, is a condition that results from the buildup of crystals in joint fluid. Unlike gout, pseudogout typically affects the large joints of the limbs instead of the big toe. Pseudogout crystals are typically made of a salt that's known as calcium pyrophosphate dihydrate. These crystals build up in the joints and can cause intense swelling and inflammation. This causes joints to become stiff and difficult to move. Pseudogout, according to Medline, is a common cause of acute (sudden onset) arthritis in one joint.
Direct Joint Damage
Pseudogout can cause permanent joint damage, the Mayo Clinic says. Some of this damage is a direct result of the crystals causing trauma to the cartilage and other connective tissues in the joint. In addition, the inflammation that pseudogout causes can also damage the joint; some of the chemicals secreted by the immune system can be toxic to healthy cells. If pseudogout is untreated, surrounding bones themselves can be weakened and damaged, which causes them to fracture more easily.
Indirect Effects
One of the hazards of chronic arthritic conditions such as pseudogout is that they can affect other joints throughout the body. If the pseudogout affects weight-bearing joints (such as the ankles), it can affect the way the patient stands and walks. This can cause weight to be distributed abnormally throughout the body and can cause additional wear and tear on joints, leading to osteoarthitis. Chronic arthritic pain can also cause patients to engage in less physical activity, which can increase their risk of heart disease and other health conditions.
