Restylane (amphadase) is a skin filler prepared from biodegradable non-animal stabilized hyaluonic acid (NASHA). The U.S. Food and Drug Administration (FDA) has approved this injectable drug for the temporary resolution of facial wrinkles and folds. Restylane increases skin volume at the site of injection, which lifts and smooths dermal lines, wrinkles and folds. Before receiving Restylane treatment, discuss the negative side effects of this substance with your doctor.
Redness
After receiving an injection of Restylane, you can develop redness (erythema) at the injection site or across your body. If you receive Restylane treatment within your facial tissue, skin redness can negatively affect your appearance. Skin redness is typically mild and resolves shortly after receiving treatment with this medical substance.
Swelling
Treatment with Restylane can cause swelling at the site of injection in certain patients. If this occurs, your skin can appear puffy or enlarged. The severity of swelling can vary from mild to moderate and may be accompanied by additional side effects, such as tenderness, pain or bruising. Swelling is typically temporary and subsides within a week following treatment, explains the Restylane USA product site.
Itching
You can develop itching or hives across your body or at the site of injection due to Restylane treatment. If such skin reactions occur, you may begin to scratch at the affected skin regions to relieve these itchy symptoms. Itching and hives caused by Restylane treatment often accompany other negative side effects of this treatment, including skin swelling or redness. These symptoms will typically subside within a week after you receive Restylane treatment.
Stomach Upset
Administration of high levels of Restylane can cause toxic side effects to develop in certain people. Symptoms of Restylane toxicity include nausea and vomiting, which may be accompanied by skin reactions, chills, dizziness and heart rate alterations. If you develop such side effects after receiving an injection of Restylane, contact your doctor immediately for further medical guidance and care.



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