Vytorin, a combination of ezetimibe and simvastatin, is a prescription medication to lower triglyceride and cholesterol levels. This medication decreases total and low-density lipoprotein, or LDL---the bad cholesterol---in two ways: it decreases the amount of cholesterol your body absorbs from food as well as the amount of cholesterol your body produces. Talk with your doctor if you have any questions or concerns regarding the adverse effects of Vytorin.
Headache
Treatment with Vytorin can cause headache symptoms, mild to severe, as a side effect. Headache symptoms are typically temporary and progressively subside with recurrent use of the medication.
Muscle Pain
You can develop constant or intermittent pain within the muscles of your arms or legs while taking Vytorin, according to Drugs.com. Such side effects can contribute to additional symptoms of weakness or fatigue. Muscle pain can range from mile to severe. Speak with your doctor immediately the pain impacts your ability to stand or walk normally.
Stomach Upset
Vytorin can lead to stomach-related side effects. Diarrhea is the most common stomach-related side effect, including frequent urges to have bowel movements, which yield loose or watery stools. Some patients may also experience nausea while taking Vytorin, according to health professionals at the Better Health Channel, an informational health website provided as a service of the Australian government. Contact your doctor immediately if you experience severe abdominal pain or vomiting.
Flu-like Symptoms
Vytorin can cause patients to experience flu-like symptoms. Typical flu-like symptoms include fever, headache, body aches, fatigue, nasal congestion, stomach upset or cough. These side effects are temporary and tend to progressively subside with recurrent use of this medication.
Respiratory Infection
Patients may be at an increased risk of developing an upper respiratory infection while taking Vytorin. In clinical trials, the U.S. Food and Drug Administration, or FDA, reported that 3.6 percent of 1,420 patients receiving Vytorin treatment experience an upper respiratory tract infection. Only 2.7 percent of 371 patients receiving a sugar pill placebo treatment reported similar side effects. Symptoms of an upper respiratory infection can include chest or nasal congestion, cough, runny nose, headache or fatigue. Such symptoms may require additional medication to resolve symptoms of this infection.



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