Estradiol is a form of estrogen, which is a natural hormone for many female sex processes in the body. Estradiol is used to treat symptoms of menopause such as hot flashes and vaginal irritation, according to Drugs.com. This medication may also be used when there is a lack of estrogen due to ovarian failure or hypogonadism. Prolonged use may increase your risk of breast or endometrial cancer. As with all medications, you should be aware of the possible side effects before taking them.
Reproductive Side Effects
The Mayo Clinic states that estradiol is associated with changes in your menstrual periods, break-through bleeding, abnormal vaginal bleeding, pain, dryness and discomfort and swollen or lumpy breast. These effects occur because estradiol is a female sex hormone, which will likely cause side effects on female sex organs. Some of these side effects will improve with use or can improve with an adjustment in dosage. However, estradiol can increase your risk for breast and endometrial cancer with long-term use. Do not hesitate to tell your doctor about these significant side effects. Frequently perform self-breast exams to look for lumps or abnormalities.
Cardiovascular System Side Effects
According to Drugs.com, estradiol 1mg tab can cause chest pain, pain that radiates from the chest to the arm or shoulder. Estradiol has been shown to increase your risk of heart attack when used over for a long term, states Drugs.com. This is a serious side effect and you should immediately call 911 if experiencing chest pain.
Nervous System Side Effects
Estradiol 1mg tabs have been shown to cause numbness and weakness on one side of the body, headache, confusion, problems with vision, speech, balance and depression, according to Drugs.com. These side effects occurs because estradiol can cause an imbalance in neurotransmitters. In addition, long-term use of estradiol has been shown to increase your risk of stroke. Seek immediate medical treatment if you are experiencing any of the neurological difficulties.



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