Diclofenac is a non-steroidal anti-inflammatory drug (NSAID) commonly prescribed to treat pain associated with inflammation and arthritis. Many users of Diclofenac experience short-term side effects in response to use and about 20 percent of all users experience some long-term side effects. While some reactions are mild, individuals taking Diclofenac should be aware of potentially dangerous long-term side effects.
Gastrointestinal Side Effects
According to the Mayo Clinic and the National Institutes of Health, the most common long-term side effects of Diclofenac use occur in the stomach or GI tract. Less dangerous side effects include bloating and gaseousness. Long-term Diclofenac use can predispose patients to peptic ulcers so it may be given in combination with misoprostol, which helps to protect the GI tract from such ulcers. Individuals over the age of 60 are most at risk for GI complications, particularly if they smoke or use alcohol regularly. Other GI effects of long-term Diclofenac use include intestinal bleeding, stomach pain and vomiting. These may be the signs of a dangerous reaction to Diclofenac and should be reported to your doctor immediately.
Skin Reactions
A number of effects on the skin have been reported with long-term Diclofenac use. These are less common and may be serious. Contact your doctor right away if you experience loosening of the skin, white or red skin discolorations, yellowing of the skin and eyes, itching, or flushing.
Cardiac Side Effects
Serious cardiac side effects can also occur in response to long-term use of Diclofenac. Such effects include increased pulse, arrhythmias, chest pains and tightening of the chest. Contact your health professional if you experience any heart-related side effects while using Diclofenac.
Liver Side Effects
Hepatic side effects of long-term Diclofenac use are rare but very serious. Your doctor may choose to monitor your liver function over the course of Diclofenac use. Some rare side effects include hepatitis as well as drug induced liver failure. Be sure to let your doctor know if you or your family has a history of liver problems before using Diclofenac.
Member Comments