Diclofenac is a commonly prescribed NSAID used in treatment of pain from arthritis, inflammation and migraine headaches. Common mild side effects of Diclofenac include bloating, intestinal gas and ringing in the ears. More serious side effects affect the gastrointestinal tract, skin and heart. A number of other rare side effects while taking Diclofenac are potentially dangerous.
Hypertension
A number of rare but serious cardiovascular side effects have been reported by individuals using Diclofenac. Such side effects include chest pains and racing heartbeat. According to FDA information listed on drugs.com, NSAIDs such as Diclofenac can also result in hypertension or increase hypertension in patients with a pre-existing condition. Let your doctor know if you or your relatives have a history of hypertension or heart disease prior to using Diclofenac. Alert your doctor immediately if you experience any troubling heart-related side effects while using Diclofenac.
Kidney (Renal) Effects
NSAIDs such as Diclofenac are known to cause renal injury with long-term use. Drugs.com explains that patients with a history of kidney problems or liver dysfunction or heart disease are at risk for developing kidney damage while using Diclofenac. Let your doctor know if you have a history of kidney, liver or heart problems before using Diclofenac.
Side Effects Requiring Emergency Attention
The Mayo Clinic lists a number of rare, dangerous side effects that can occur as a result of a Diclofenac overdose. Signs include agitation, blurry vision, confusion, blue lips or skin and rapid weight gain. Symptoms of allergic reaction such as wheezing, puffiness of the skin and faintness are also very serious. Seek emergency attention if you experience these or any other distressing side effects of Diclofenac.
Liver (Hepatic) Side Effects
Diclofenac use can also lead to liver dysfunction. According to the U.S. Food and Drug Administration, liver failure may occur at any time while using Diclofenac. Doctors should monitor patients for liver function during Diclofenac use, starting at one month after the start of treatment.



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