Fluoxetine HCL (Prozac) is a commonly prescribed medication used to treat depression. According to Drugs.com, fluoxetine affects a certain chemical in the brain that may become unbalanced and cause depression, panic, anxiety or obsessive-compulsive symptoms. In addition, fluoxetine is commonly combined with olanzapine to treat the depression aspect of bipolar disorder, states the Mayo Clinic. As with all medications, you should be aware the possible associated side effects and when to seek treatment for them.
Nervous System Side Effects
Fluoxetine works by altering the levels of a certain neurotransmitter in your brain. This same neurotransmitter plays a role in other brain functions; therefore, altering its levels will have other nervous system side effects. Be cautious of headache, trouble concentrating, memory problems, weakness, confusion, hallucinations, fainting, seizure, loss of coordination, drowsiness, dizziness, sleep problems, decreased sex drive, impotence and difficulty having an orgasm, according to Drugs.com. Seek immediate medical treatment if you have hallucinations, fainting or seizure. These side effects will likely improve with continued use of fluoxetine. However, always let your doctor know that you are having these side effects.
Digestive Tract Side Effects
Fluoxetine may have a negative effect on your digestive tract. Neurotransmitters are also responsible for making sure your digestive system functions correctly. Thus, altering these chemical signals can result in side effects. Let your doctor know if you experience nausea, vomiting, diarrhea, loss of appetite, constipation, upset stomach, weight changes or increased appetite. None of these effects constitute an emergency; however, never hesitate to see your doctor if they become troublesome for you.
Skin Side Effects
Fluoxetine has been known to cause skin rash, hives, itching, blistering and peeling. These symptoms will likely improve as your body adjusts to the medication. However, if you experience a sudden rash associated with difficulty breathing, swelling of the face, lips, tongue or throat, seek immediate medical treatment. Do not use creams to treat these side effects. Instead, let your doctor know so he can adjust your dosage or prescribe a different medication.



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