An erosion in the lining of the first part of the small intestine is called a duodenal ulcer. Symptoms of a duodenal ulcer include abdominal pain, bloody stools and nausea. Ulcers are usually diagnosed by the patent's symptoms, endoscopy or by barium X-ray. Treatment depends on the severity of the ulcer and the patient's overall health.
Antibiotic Therapy
Most ulcers are believed to be caused by the organism H. pylori. Two different antibiotics to kill H. pylori, such as clarithromycin (Biaxin), amoxicillin, tetracycline, or metronidazole (Flagyl) may be used to treat a duodenal ulcer, reports the Medline website. Treatment usually lasts approximately five to 14 days.
Proton Pump Inhibitors
According to Medline, proton pump inhibitors such as omeprazole (Prilosec), lansoprazole (Prevacid) or esomeprazole (Nexium) are used in the treatment of duodenal ulcers. Proton pump inhibitors may be used in conjunction with antibiotics. These drugs work by decreasing the stomach's acid production.
Pepto-Bismol
Sometimes bismuth subsalicylate (Pepto-Bismol) is used in combination with antibiotics to treat a duodenal ulcer, according to the Merck website. This medication works by neutralizing or reducing stomach acid to promote healing of the ulcer. This medication may be used for up to four to eight weeks depending on the severity of the condition.
Diet and Lifestyle Modification
Stress and diet may be linked to the development of an ulcer. Certain exercises or techniques, such as yoga, meditation or mild exercise may help to alleviate stress. Avoiding fried or spicy foods may help to heal an existing ulcer.


