Methadone is a prescription narcotic (opiate) medication indicated for the relief of moderate to severe pain and the management of opiate withdrawal symptoms in patients enrolled in a drug treatment program. This medication can be habit-forming and should only be taken orally as prescribed by your doctor.
Stomach Upset
Nausea and vomiting are the most common physical effects of this medication and may be accompanied by difficult bowel movements (constipation). You can also develop stomach pain, cramping or bloating after taking methadone. Certain patients experience a dry mouth, which can cause increased thirst or sore throat symptoms. To prevent these effects, your doctor may recommend eating a small meal or snack before taking a dose of this medication.
Body Weight Changes
Patients who experience physical effects of stomach upset may also experience decreased appetite, which can lead to weight loss. Some patients experience weight gain during methadone treatment, which may be the result of water retention within your arms, legs or feet. Discuss body weight changes with your doctor to ensure that you receive appropriate treatment.
Drowsiness
Physical effects of drowsiness may also be accompanied by shallow breathing, dizziness, lightheadedness, muscle weakness or headache. Do not drive or participate in potentially hazardous activities immediately after taking methadone as these side effects can significantly decrease your reaction time. Your doctor should be contacted immediately if you faint or lose consciousness while taking methadone.
Increased Sweating
You may notice that your pajamas or bed linens feel damp when you wake up. Night sweats experienced during methadone treatment can cause you to wake up intermittently throughout the night, which can contribute to daytime drowsiness or weakness. You may also notice that your skin appears abnormally flushed (red) or itchy. Swelling of the skin should be immediately reported to your doctor, as it may be indicative of an allergic reaction.
Menstrual Cycle Changes
Women who take methadone can develop menstrual cycle changes as a physical effect of treatment, explain health professionals at the Center for Substance Abuse Research at the University of Maryland in Baltimore. A woman may miss a period or experience a heavier, more painful menstrual cycle. If you miss your period during methadone treatment, contact your doctor for further evaluation to ensure that you are not pregnant.
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