St. John's wort, otherwise known as Hypericum perforatum, was first recorded for medicinal use in ancient Greece. It has previously been used as a sedative to treat nerve pain as well as a balm for wounds, burns and insect bites. Today, St. John's wort is used for depression, anxiety and sleep disorders. Recent studies through the Mayo Clinic suggest that side effects occur in 1 to 3 percent of patients taking St. John's wort.
Common Reactions
According to the Mayo Clinic, the most common biological reactions include gastrointestinal upset, fatigue, sedation, restlessness, anxiety, sexual dysfunction, dizziness, headache and dry mouth. A smaller study associated St. John's wort with an elevated thyroid stimulating hormone levels.
Psychiatric Reactions
St. John's wort is most commonly taken for depression. Side effects have been seen when combined with antidepressants, including nausea, anxiety, headache and confusion. The Mayo Clinic reports that St. John's wort may also cause psychiatric symptoms, such as suicidal and homicidal thoughts. Anyone who may be depressed should see a health care provider about the best medication and supplementation for her situation.
Allergic Reactions
Some studies have shown allergic skin reactions, including a rash and itching. Another skin reaction is sensitivity to sunlight; St. John's wort can increase the likelihood of a sunburn. If you have any type of allergic reaction, it is important to contact your health care provider immediately.
Drug Interactions
St. John's wort has been shown to interact with certain medications, supplements and herbs. The National Institute of Health (NIH) cautions taking St. John's wort with birth control pills, anticoagulants, drugs used to treat cancer and HIV infection, among others. Research shows that St. John's wort affects the speed of a drug's breakdown by either increasing or slowing the way the body processes the medication. Consult with a physician if you are on prescription medication and are considering taking St. John's wort and any other alternative therapies, including supplements.
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