The Effects of Methotrexate

The Effects of Methotrexate
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Methotrexate is used to treat certain cancers of the breast, skin, head, neck and lungs, as well as psoriasis and rheumatoid arthritis, states Drug Information Online. It comes in tablet form. If this medication is not taken properly according to your doctor's instruction, it may cause serious side effects. It may only be taken once or twice per week, depending on the severity of your condition. Taking additional doses may cause serious or life-threatening side effects on your lungs, kidneys, liver or immune system.

Nausea and Vomiting

You may experience nausea and vomiting while on methotrexate. These side effects may diminish over time as your body has a chance to get used to this medication. Avoid spicy foods and eat a bland diet. Eating smaller meals more frequently may help to alleviate nausea.

Headache and Dizziness

Headache and dizziness are common side effects of methotrexate. You may want to use caution before driving or operating machinery until you know how this medication will affect you. You can treat your headache with acetaminophen as per your doctor's consent.

Bleeding Gums

You may experience bleeding gums while taking methotrexate. Be sure to use a softer bristle toothbrush. Consult with your dentist if you are experiencing bleeding gums.

Gastrointestinal Complications

Methotrexate may cause damage to the lining of your mouth, stomach or intestines, states Medline. Symptoms of gastrointestinal illness include diarrhea, mouth sores, bloody, tarry or black stools or vomit that is dark in color and resembles used coffee grounds. Report these symptoms to your physician immediately.

Serious Side Effects

Methotrexate can cause serious side effects such as sudden loss of vision, seizures,
confusion, weakness, difficulty moving one or both sides of the body or loss of consciousness, reports Medline. If you experience any of these side effects, seek emergency medical attention.

References

Article reviewed by Carrie Last updated on: Mar 12, 2010

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