TriLyte is a medication that is used prior to a colonoscopy to clean out the intestines. A colonoscopy is a procedure used to diagnose ailments of your bowels such as colon cancer. The Mayo Clinic says it is performed with a long, flexible tube, or colonoscope, that is guided into the rectum and through the large intestines. The tube contains a video camera that allows the doctor to see any problems that may exist. TriLyte may be administered as a drink or via a tube through the nose into the stomach.
Bloating
TriLyte, a mixture of sodium chloride, potassium chloride, sodium bicarbonate and PEG-3350 or polyethylene glycol 3350, commonly produces a sensation of bloating. RxList.com indicates that nearly 50 percent of those given the substance report feeling bloated. This is a common and non-serious side effects of taking TriLyte. This side effect should not continue beyond the use of the medication prior to the colonoscopy.
Nausea and Vomiting
TriLyte also can create a sensation of queasiness in your stomach. Because fasting is recommended for at least 4 hours prior to taking TriLyte, you may feel nauseous even without having eaten anything. In some cases, vomiting will occur. The medical term for this non-serious temporary side effect is emesis. Any nausea and vomiting should clear up following the procedure.
Cramps
Drinking TriLyte also can produce cramps in your abdomen. Fortunately, this side effect should subside as the medication works its way out of your body following the colonoscopy.
Rectal Irritation
TriLyte can cause you to feel irritation in the rectal area in addition to the discomfort caused by the colonoscopy procedure. RxList.com states that this side effect will diminish quickly. If irritation worsens or persists, your doctor should be consulted.



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