Centella asiatica, more commonly known as gotu kola and Indian pennywort, is an herbal remedy. It's primarily used to treat disorders of arteries and veins in the arms and legs (peripheral vascular disease) and varicose veins. A topical solution also may relieve symptoms of psoriasis and help heal minor wounds. Numerous side effects are possible but rare.
Minor Side Effects
Topical use of Centella asiatica can result in a skin allergy reaction with burning sensations. When taken orally, Centella asiatica may cause dizziness, headache, upset stomach, nausea, skin sensitivity to sun and extreme drowsiness. These side effects tend to occur with high doses of the herb.
Diuretic Effects
Centella asiatica appears to have diuretic effects and helps eliminate excess fluid from the body. This can cause more frequent urination than usual. Taking diuretic medications and this herb together can cause too much fluid loss and disrupt electrolyte balance, as explained by the University of Maryland Medical Center (UMMC). People also should not take Centella asiatica with other herbs that have diuretic effects, including astragalus, green tea and Ginkgo biloba.
Liver Effects
The UMMC recommends consulting with a doctor after using this herb for six weeks, and perhaps taking a two-week break. People with liver disease, or who take medications that affect the liver such as statin drugs or acetaminophen, should not take Centella asiatica. Signs of liver problems include lack of appetite, nausea, stomach pain, low fever, dark urine, clay-colored stools and jaundice.
Allergic Reaction
Drugs.com. says some signs of an allergic reaction include a rash or hives, trouble breathing, tightness or pain in the chest, difficulty swallowing, swollen skin and facial or mouth swelling. An allergic reaction to this herb calls for immediate medical attention.
Effects Seen in Animal Studies
A main component of Centella asiatica called asiaticoside has been associated with tumor growth in mice. Although this effect has not been indicated in humans, the UMMC recommends that anyone with a history of precancerous or cancerous skin lesions should not use this herb. Additionally, Centella asiatica increased blood sugar levels and cholesterol levels in animal studies, so people with diabetes or high cholesterol may want to talk with a doctor before taking this herb.
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