Glucocorticoid Resistance

What Is the Purpose of Cortisol?

Cortisol is the body’s main stress hormone, which is produced in the adrenal glands, located adjacent to the kidneys. It is synthesized from cholesterol and acts through specific intracellular receptors to affect numerous physiologic...

Medicines That Cause Diabetes

Diabetes is a disease in which the body is unable to remove glucose, a type of sugar, from the blood. Normally, when levels of glucose in the blood rise the pancreas secretes a hormone called insulin that causes fat and muscle cells to absorb...

High Levels of Glucocorticoids & Glucose Metabolism

Glucocorticoids are hormones produced by your adrenal glands. They affect cellular processes in nearly all body tissues, particularly glucose metabolism in liver, muscle and fat tissue. Although cortisol is necessary for proper response to...

Clinical Drug Classes That Cause Secondary Diabetes

Secondary diabetes occurs when the level of glucose, a type of sugar, in the blood is too high as the result of some other disease or condition. Normally, the pancreas secretes insulin in response to rising glucose levels, which causes cells to...

The Effects of DHEA on Muscle

Dehydroepiandrosterone, or DHEA, is a steroid hormone produced by the adrenal glands, gonads and brain. It is a precursor of other steroid hormones including estrogens and testosterone. Many studies have been conducted to determine whether DHEA...