What is Alpha-lipoic Acid?
Folate and folic acid are forms of a water-soluble B vitamin. Folate occurs naturally in food and folic acid is the synthetic form of this vitamin. Folic acid is well-tolerated in amounts found in fortified foods and supplements, in doses less than 1000mcg per day.
Side Effects
Alopecia (hair loss), bloating, bitter taste, bronchospasm, change in sleep patterns, confusion, cramps, diarrhea, excitability, gas, impaired judgment, itching, irritability, nausea, overactivity, psychotic behavior, pruritus, seizure, skin flushing, stomatitis, swelling, hives, vivid dreams, zinc depletion.
Reactions / Interactions
Alcohol, antacids, aminosalicylic acid (para-aminosalicylic acid, PAS, paser), antibiotics, aspirin, birth control pills, carbamazepine (Tegretol®), chloramphenicol, cholestyramine (Questran®), colestipol (colestid®), cycloserine (Seromycin Pulvules®), diuretics, estrogens, H2 blockers, metformin (Glucophage®), methotrexate, methylprednisolone (Solu-Medrol®), nonsteroidal anti-inflammatory drugs (NSAIDs), pancreatic enzymes, pancrelipase, pancreatin, pentamidine (pentacarinat®, Pentam 300®), ...
What is Alpha-lipoic Acid?
Folate and folic acid are forms of a water-soluble B vitamin. Folate occurs naturally in food and folic acid is the synthetic form of this vitamin. Folic acid is well-tolerated in amounts found in fortified foods and supplements, in doses less than 1000mcg per day.
Side Effects
Alopecia (hair loss), bloating, bitter taste, bronchospasm, change in sleep patterns, confusion, cramps, diarrhea, excitability, gas, impaired judgment, itching, irritability, nausea, overactivity, psychotic behavior, pruritus, seizure, skin flushing, stomatitis, swelling, hives, vivid dreams, zinc depletion.
Reactions / Interactions
Alcohol, antacids, aminosalicylic acid (para-aminosalicylic acid, PAS, paser), antibiotics, aspirin, birth control pills, carbamazepine (Tegretol®), chloramphenicol, cholestyramine (Questran®), colestipol (colestid®), cycloserine (Seromycin Pulvules®), diuretics, estrogens, H2 blockers, metformin (Glucophage®), methotrexate, methylprednisolone (Solu-Medrol®), nonsteroidal anti-inflammatory drugs (NSAIDs), pancreatic enzymes, pancrelipase, pancreatin, pentamidine (pentacarinat®, Pentam 300®), phenobarbital (Luminal®), primidone (Mysoline®), phenytoin (Dilantin®), proton pump inhibitors (PPIs), pyrimethamine (Daraprim®), seizure drugs, sulfasalazine (Azulfidine®), triamterene (Dyrenium®), trimethoprim (Trimpex®), nicotine (cigarettes), vitamin B12, zinc, other herbs and supplements with similar effects.
Safety
Avoid if allergic or hypersensitive to folate or any of the product ingredients. It is recommended that pregnant women consume 400 micrograms daily in order to reduce the risk of the fetus developing a defect. Folate is likely safe if breastfeeding.
Dosage
Adults (18 years and older)
U.S. Recommended Dietary Allowance (RDA) for adults: 400 micrograms daily; 500 micrograms daily for breastfeeding women; 600 micrograms daily for pregnant adult women.
Tolerable upper intake levels (UL) per day: The UL is the highest amount that can be taken daily without serious side effects. The UL is 800 micrograms daily for people 14-18 years-old (including pregnant or breastfeeding women); and 1,000 micrograms for adults19 years and older (including pregnant or breastfeeding women).
Children (18 years and younger)
U.S. Recommended Dietary Allowance (RDA) or Adequate for children:
For infants 0-6 months-old the AI is 65 micrograms per day; for infants 7-12 months-old the recommended dose is 80 micrograms per day; for children 1-3 years-old the RDA is 150 micrograms per day; for children 4-8 years-old the RDA is 200 micrograms per day; for children 9-13 years-old the RDA is 300 micrograms per day.
Tolerable upper intake levels (UL) per day: The UL is the highest amount that can be taken daily without serious side effects. For children 1-3 years-old the UL is 300 micrograms; for children 4-8 years-old the UL is 400 micrograms; for children 9-13 years-old the UL is 600 micrograms; for adolescents 14-18 years-old the UL is 800 micrograms.
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While some complementary and alternative techniques have been studied scientifically, high-quality data regarding safety, effectiveness, and mechanism of action are limited or controversial for most therapies. Whenever possible, it is recommended that practitioners be licensed by a recognized professional organization that adheres to clearly published standards. In addition, before starting a new technique or engaging a practitioner, it is recommended that patients speak with their primary healthcare provider(s). Potential benefits, risks (including financial costs), and alternatives should be carefully considered. The below monograph is designed to provide historical background and an overview of clinically-oriented research, and neither advocates for or against the use of a particular therapy. The information in this monograph is intended for informational purposes only, and is meant to help users better understand health concerns. Information is based on review of scientific research data, historical practice patterns, and clinical experience. This information should not be interpreted as specific medical advice. Users should consult with a qualified healthcare provider for specific questions regarding therapies, diagnosis and/or health conditions, prior to making therapeutic decisions.
