What is Thiamin?
Thiamin (also spelled "thiamine") is a water-soluble B-complex vitamin. It is also known as vitamin B1 or aneurine. Thiamin is involved in nervous system and muscle functioning, enzyme processes, breakdown of carbohydrates and production of hydrochloric acid (which is needed for digestion). There is very little thiamin stored in the body, and depletion can occur quickly. Severe chronic thiamin deficiency can cause potentially serious complications involving the nervous system/brain, muscles, ...
Side Effects
Burning, drowsiness, itching, contact dermatitis, muscle relaxation, severe allergic reaction, skin irritation.
Reactions / Interactions
Phenytoin (Dilantin), antacids, barbiturates, diuretics, tobacco, neuromuscular blocking agents (NMBAs), antibiotics, birth control pills, fluorouracil, metformin (Glucophage), betel nut, horsetail, alcohol, carbonated drinks, coffee, tea, raw seafood, and other herbs or supplements with similar effects.
What is Thiamin?
Thiamin (also spelled "thiamine") is a water-soluble B-complex vitamin. It is also known as vitamin B1 or aneurine. Thiamin is involved in nervous system and muscle functioning, enzyme processes, breakdown of carbohydrates and production of hydrochloric acid (which is needed for digestion). There is very little thiamin stored in the body, and depletion can occur quickly. Severe chronic thiamin deficiency can cause potentially serious complications involving the nervous system/brain, muscles, heart, and gastrointestinal system.
Side Effects
Burning, drowsiness, itching, contact dermatitis, muscle relaxation, severe allergic reaction, skin irritation.
Reactions / Interactions
Phenytoin (Dilantin), antacids, barbiturates, diuretics, tobacco, neuromuscular blocking agents (NMBAs), antibiotics, birth control pills, fluorouracil, metformin (Glucophage), betel nut, horsetail, alcohol, carbonated drinks, coffee, tea, raw seafood, and other herbs or supplements with similar effects.
Safety
Thiamin is generally considered safe and relatively nontoxic, even at high doses. Avoid if allergic or hypersensitive to thiamin.
Thiamin appears safe if pregnant or breastfeeding. The U.S. Recommended Daily Allowance (RDA) for pregnant or breastfeeding women is 1.4mg taken by mouth.
Dosage
Beef, Brewer's yeast, legumes (beans, lentils), milk, nuts, oats, oranges, pork, rice, seeds, wheat, whole grain cereals, and yeast. In industrialized countries, foods made with white rice or white flour are often fortified with thiamin (because most of the naturally occurring thiamin is lost during the refinement process).
Adults (18 years and older)
U.S. Recommended Daily Allowance (RDA): The RDA for adults ages 19 years and older is 1.2mg daily for males and 1.1mg daily for females, taken by mouth. The RDA for pregnant or breastfeeding women of any age is 1.4mg daily, taken by mouth. 1-2mg daily is sometimes used as a dietary supplement.
Children (18 years and younger)
Adequate Intake (AI) / U.S. Recommended Daily Allowance (RDA): For infants ages 0-6 months the AI is 0.2mg; for infants 7-12 months the AI is 0.3mg; for children 1-3 years the RDA is 0.5mg; for children 4-8 years the RDA is 0.6mg; for children ages 9-13 years the RDA is 0.9mg; for males ages 14-18 years the RDA is 1.2mg; for females ages 14-18 years the RDA is 1mg, taken by mouth. The RDA for pregnant or breastfeeding women of any age is 1.4mg daily, taken by mouth.
Evidence
Condition: Thiamin deficiency Grade: A
Condition: Metabolic disorders Grade: A
Condition: Acute alcohol withdrawal Grade: B
Condition: Total parenteral nutrition (TPN) Grade: B
Condition: Alzheimer's disease Grade: C
Condition: Athletic performance Grade: C
Condition: Cancer Grade: C
Condition: Cataract prevention Grade: C
Condition: Coma/hypothermia of unknown origin Grade: C
Condition: Crohn's disease Grade: C
Condition: Didmoad (Wolfram) syndrome Grade: C
Condition: Heart failure (cardiomyopathy) Grade: C
Condition: Pyruvate dehydrogenase deficiency (PDH) Grade: C
Condition: Subclinical thiamin deficiency in the elderly Grade: C
Condition: Hip fracture Grade: D
Disclaimer: These uses have been tested in humans or animals. Safety and effectiveness have not always been proven. Some of these conditions are potentially serious, and should be evaluated by a qualified healthcare provider.
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While some complementary and alternative techniques have been studied scientifically, high-quality data regarding safety, effectiveness, and mechanism of action are limited or controversial for most therapies. Whenever possible, it is recommended that practitioners be licensed by a recognized professional organization that adheres to clearly published standards. In addition, before starting a new technique or engaging a practitioner, it is recommended that patients speak with their primary healthcare provider(s). Potential benefits, risks (including financial costs), and alternatives should be carefully considered. The below monograph is designed to provide historical background and an overview of clinically-oriented research, and neither advocates for or against the use of a particular therapy. The information in this monograph is intended for informational purposes only, and is meant to help users better understand health concerns. Information is based on review of scientific research data, historical practice patterns, and clinical experience. This information should not be interpreted as specific medical advice. Users should consult with a qualified healthcare provider for specific questions regarding therapies, diagnosis and/or health conditions, prior to making therapeutic decisions.