What is Chondroitin Sulfate?
Chondroitin was first extracted and purified in the 1960s. Today it is manufactured from natural sources (like shark, beef cartilage or bovine trachea) or by artificial means. Chondroitin is commonly used with glucosamine for improving symptoms and possibly reversing the process of Osteoarthritis.
Side Effects
Headache, motor uneasiness, euphoria, hives, rash, photosensitivity, hair loss, breathing problems, tightness in the throat or chest, worsening of asthma, chest pain, increased blood pressure, edema (swelling), gastrointestinal pain/upset stomach, nausea, diarrhea, constipation, transaminitis (liver enzyme leakage without liver damaging consequences in patients receiving drug therapy of any kind), increased risk of bleeding, bone marrow suppression, eyelid edema.
Reactions / Interactions
Blood thinners such as warfarin (Coumadin®) or heparin, anti-platelet drugs such as clopidogrel (like Plavix®), non-steroidal anti-inflammatories (NSAIDS) such as ibuprofen (like Motrin® or Advil®) and naproxen (like Naprosyn® or Aleve®), hyaluronidase agents (attracted to water), agents associated with sun sensitivity, or herbs or supplements with similar effects (like Ginkgo biloba ,
garlic, saw palmetto, or alfalfa).
What is Chondroitin Sulfate?
Chondroitin was first extracted and purified in the 1960s. Today it is manufactured from natural sources (like shark, beef cartilage or bovine trachea) or by artificial means. Chondroitin is commonly used with glucosamine for improving symptoms and possibly reversing the process of Osteoarthritis.
Side Effects
Headache, motor uneasiness, euphoria, hives, rash, photosensitivity, hair loss, breathing problems, tightness in the throat or chest, worsening of asthma, chest pain, increased blood pressure, edema (swelling), gastrointestinal pain/upset stomach, nausea, diarrhea, constipation, transaminitis (liver enzyme leakage without liver damaging consequences in patients receiving drug therapy of any kind), increased risk of bleeding, bone marrow suppression, eyelid edema.
Reactions / Interactions
Blood thinners such as warfarin (Coumadin®) or heparin, anti-platelet drugs such as clopidogrel (like Plavix®), non-steroidal anti-inflammatories (NSAIDS) such as ibuprofen (like Motrin® or Advil®) and naproxen (like Naprosyn® or Aleve®), hyaluronidase agents (attracted to water), agents associated with sun sensitivity, or herbs or supplements with similar effects (like Ginkgo biloba,
garlic, saw palmetto, or alfalfa).
Safety
Use cautiously if allergic or hypersensitive to chondroitin sulfate products and with shellfish allergy. Use cautiously with bleeding disorders and with blood-thinners like warfarin (like Coumadin®). Avoid with prostate cancer or increased risk of prostate cancer. Avoid if pregnant or breastfeeding.
Dosage
Adults (18 years and older)
Doses of 200-400 milligrams twice to three times daily, or 800-1,200 milligrams once daily have been used. Higher doses (up to 2, 000 milligrams) may be equally as effective.
Children (younger than 18 years)
Not enough scientific data available.
Evidence
Condition: Osteoarthritis Grade: A
Condition: Bladder control Grade: B
Condition: Coronary artery disease (secondary prevention) Grade: C
Condition: Interstitial cystitis Grade: C
Condition: Iron absorption enhancement Grade: C
Condition: Ophthalmologic (eye) uses Grade: C
Condition: Psoriasis Grade: C
Condition: Muscle soreness (delayed onset) Grade: D
Disclaimer: These uses have been tested in humans or animals. Safety and effectiveness have not always been proven. Some of these conditions are potentially serious, and should be evaluated by a qualified healthcare provider.
"Content Licensed by Natural Standard. Copyright 2009 by Natural Standard Corporation."
While some complementary and alternative techniques have been studied scientifically, high-quality data regarding safety, effectiveness, and mechanism of action are limited or controversial for most therapies. Whenever possible, it is recommended that practitioners be licensed by a recognized professional organization that adheres to clearly published standards. In addition, before starting a new technique or engaging a practitioner, it is recommended that patients speak with their primary healthcare provider(s). Potential benefits, risks (including financial costs), and alternatives should be carefully considered. The below monograph is designed to provide historical background and an overview of clinically-oriented research, and neither advocates for or against the use of a particular therapy. The information in this monograph is intended for informational purposes only, and is meant to help users better understand health concerns. Information is based on review of scientific research data, historical practice patterns, and clinical experience. This information should not be interpreted as specific medical advice. Users should consult with a qualified healthcare provider for specific questions regarding therapies, diagnosis and/or health conditions, prior to making therapeutic decisions.
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