What is Riboflavin?
Riboflavin is a water-soluble vitamin. It is needed for normal cell function, growth, and energy production. Small amounts of riboflavin are found in most animal and plant tissues. Healthy individuals who eat a balanced diet rarely need riboflavin supplements. Milk (and other dairy products), eggs, enriched cereals/grains, meats, liver and green vegetables (like asparagus or broccoli) are especially good sources of riboflavin.
Side Effects
Burning/prickling sensation, discolored urine, itching, numbness.
Reactions / Interactions
Anticholinergics, drugs for malaria, doxorubicin (Adriamycin®), methotrexate, birth control pills, phenobarbitol, phenothiazine antipsychotic drugs (like chlorpromazine), phenytoin (DIlantin®), probenecid, tamoxifen, tetracycline, thiazide diuretics, tricyclic antidepressants (like imipramine, desimpramine, amitriptyline or nortriptyline), b-complex vitamins, and other herbs or supplements with similar effects.
What is Riboflavin?
Riboflavin is a water-soluble vitamin. It is needed for normal cell function, growth, and energy production. Small amounts of riboflavin are found in most animal and plant tissues. Healthy individuals who eat a balanced diet rarely need riboflavin supplements. Milk (and other dairy products), eggs, enriched cereals/grains, meats, liver and green vegetables (like asparagus or broccoli) are especially good sources of riboflavin.
Side Effects
Burning/prickling sensation, discolored urine, itching, numbness.
Reactions / Interactions
Anticholinergics, drugs for malaria, doxorubicin (Adriamycin®), methotrexate, birth control pills, phenobarbitol, phenothiazine antipsychotic drugs (like chlorpromazine), phenytoin (DIlantin®), probenecid, tamoxifen, tetracycline, thiazide diuretics, tricyclic antidepressants (like imipramine, desimpramine, amitriptyline or nortriptyline), b-complex vitamins, and other herbs or supplements with similar effects.
Safety
Avoid if allergic or hypersensitive to riboflavin. Since the amount of riboflavin a human can absorb is limited, riboflavin is generally considered safe. Riboflavin is generally regarded as being safe during pregnancy and breastfeeding. The U.S. Recommended Daily Allowance (RDA) for riboflavin in pregnant women is higher than for non-pregnant women, and is 1.4mg daily (1.6mg for breastfeeding women).
Dosage
Adults (18 years and older)
U.S. Recommended Dietary Allowance (RDA) for adults (taken by mouth): 1.0mg for female teenagers (14-18 years old); 1.3mg for male teenagers (14-18 years old); 1.1mg for female adults (older than 18 years); 1.3mg for male adults (older than 18 years); 1.4mg for pregnant women (any age); 1.6mg for breastfeeding women (any age).
Children (18 years and younger)
U.S. Recommended Dietary Allowance (RDA) for infants and children (taken by mouth): 0.3mg for 0-6 months old; 0.4mg for 7-12 months old; 0.5mg for 1-3 years old; 0.6mg for 4-8 years old; 0.9mg for 9-13 years old; 1.0mg for female teenagers (14-18 years old); 1.3mg for male teenagers (14-18 years old).
Evidence
Condition: Jaundice (yellowing of skin and eyes) in newborn infants Grade: A
Condition: Riboflavin deficiency (ariboflavinosis) Grade: A
Condition: Anemia (iron deficiency) Grade: C
Condition: Anorexia/bulimia (eating disorders) Grade: C
Condition: Cancer of the esophagus Grade: C
Condition: Cataracts Grade: C
Condition: Depression Grade: C
Condition: Ethylmalonic encephalopathy Grade: C
Condition: Malaria Grade: C
Condition: Mental function Grade: C
Condition: Migraine headache prevention Grade: C
Condition: Preeclampsia (high blood pressure during pregnancy) Grade: C
Disclaimer: These uses have been tested in humans or animals. Safety and effectiveness have not always been proven. Some of these conditions are potentially serious, and should be evaluated by a qualified healthcare provider.
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