MSM (Methylsulfonylmethane)

What is MSM (Methylsulfonylmethane)?

Methylsulfonylmethane, or MSM, is a form of organic sulfur that occurs naturally in a variety of fruits, vegetables, grains, and animals. No evidence suggests MSM is a necessary part of a normal diet. In one clinical trial, MSM seemed to improve symptoms of allergic rhinitis and osteoarthritis. However, more high quality research using MSM as a monotherapy is necessary to define its role in treating these conditions.

Side Effects

Mild gastrointestinal discomfort.

Reactions / Interactions

Anti inflammatory agents, antioxidants, and herbs and supplements with similar effects.

Safety

Avoid if allergic or hypersensitive to MSM. Long-term effects of supplementation with MSM have not been examined. Avoid if pregnant or breastfeeding.

Dosage

Adults (18 years and older)

500-8,000 milligrams daily with or after meals for 30 days to 12 weeks has been studied.

Children (18 years and younger)

Not enough scientific data available.

Evidence

Condition: Allergic rhinitis Grade: C

Condition: Osteoarthritis Grade: C

Disclaimer: These uses have been tested in humans or animals. Safety and effectiveness have not always been proven. Some of these conditions are potentially serious, and should be evaluated by a qualified healthcare provider.

Content provided by:

"Content Licensed by Natural Standard. Copyright 2009 by Natural Standard Corporation."

While some complementary and alternative techniques have been studied scientifically, high-quality data regarding safety, effectiveness, and mechanism of action are limited or controversial for most therapies. Whenever possible, it is recommended that practitioners be licensed by a recognized professional organization that adheres to clearly published standards. In addition, before starting a new technique or engaging a practitioner, it is recommended that patients speak with their primary healthcare provider(s). Potential benefits, risks (including financial costs), and alternatives should be carefully considered. The below monograph is designed to provide historical background and an overview of clinically-oriented research, and neither advocates for or against the use of a particular therapy. The information in this monograph is intended for informational purposes only, and is meant to help users better understand health concerns. Information is based on review of scientific research data, historical practice patterns, and clinical experience. This information should not be interpreted as specific medical advice. Users should consult with a qualified healthcare provider for specific questions regarding therapies, diagnosis and/or health conditions, prior to making therapeutic decisions.