Hi, I'm Alice Holland, and I'm going to go over running and having a degenerative medial meniscus. Most people with degenerative conditions in their knee often wonder whether they can run again. I'm going to go over whether that is safe and whether it's not. With a degenerative joint you want to make some key specific modifications to your running. You might want to cross off half marathons and marathons off your list. They are just too much weight bearing. Also change your terrain, go to trail, treadmill or track. That would decrease the load on your joint. The second thing you want to do is avoid cutting and turning too fast. When you are running, slow down to walking speed and then turn directions if you have to. This would allow your knee to attenuate to the forces and also it would decrease the amount of lateral instability in your knee. You also want to cross train with biking, swimming or elliptical work. This would allow your knee to take a break from all the weight bearing it's doing while you are running. Now if you made the modifications to your running and you are still having sharp pain in your knee, the osteoarthritis in your joint would not allow you to run any longer. You might have to switch to a different sport, that is much less weight bearing.