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Precautions for Grapefruit Seed Extract

author image Anne Reichert
Anne Reichert is a health and wellness advisor promoting stress reduction and coaching personal strength building on multi-dimensional levels throughout her local Boulder, Colo., community with audiences ranging nationwide. Reichert enjoys creative intervention for health and emotional imbalances on a holistic level, with more than 10 years experience as a biofeedback practitioner and stress reduction specialist.
Precautions for Grapefruit Seed Extract
A closeup of a slice of grapefruit with seed. Photo Credit: Bob Cornelis/Photolibrary/Getty Images

Allergy-prone individuals who avoid grains, such as wheat, often benefit from the mild effects of using grapefruit seed extract for intestinal problems and constipation. A variety of physical conditions, including acne, allergies, body odor, gastrointestinal infections, gingivitis, sinusitis and Candida have been treated with the use of the supplement.

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Ingesting extracts that contain citrus should be recognized for potential adverse effects before use.


Pill Caution
Pill Caution

Grapefruit seed extract is a compound made from the seed, pulp and rind of the fruit in most cases. In Chinese medicine, citrus fruits are contraindicated when combined with certain herbs. Additionally, western medicine cautions avoidance of large quantities of grapefruit when taking synthetic pharmaceuticals, such as Lipitor, as a daily regime. Research interaction concerns with any supplement, drug or remedy before combining.

Physical Conditions

Diagnosed Conditions
Diagnosed Conditions

Certain illness may cause the body to adversely react to the stimulating effects of grapefruit seed extract. Although grapefruit seed extract is beneficial in healing numerous intestinal conditions such as parasite invasion and gastrointestinal infections, the U.S. National Library of Medicine suggests avoiding any part of citrus fruits for specific conditions such as Crohn's disease and ulcerative colitis.

Possible Effects

Grapefruit seed extract is considered generally safe, yet differs mildly in its effects on each Individual. To some, the fiber content has a laxative effect, and with others, there is an increase in energy due to productive internal warfare from its antimicrobial, antibacterial and antiviral effects. Starting with only a small dosage to monitor your body's response, decreases the chance of undesirable effects.


Water Consumption
Water Consumption

Drink plenty of water when taking this product. As with any fiber supplement, due to expansion in the intestinal tract, water is necessary to provide proper lubrication for movement. Dry bowels cause pain and inflammation and often worsen existing irritations or conditions.

Due to the antibacterial, antiviral and antifungal properties of grapefruit seed extract, a well maintained hydration level is beneficial to support the transport of toxic debris through the elimination system in the body for proper disposal.

Food combinations

Salty Spice
Salty Spice

Combining highly acidic beverages or foods with grapefruit seed extract may cause upset stomach or overly acidic states. Avoid consuming large quantities of products such as coffee, soda, alcohol or salty foods at the time of ingesting grapefruit seed extract to minimize excess acid production.

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